Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.
4 affiliations
- 1From the Department of Plastic, Reconstructive and Aesthetic Surgery, Hospital of the Brothers of St. John of God, Paracelsus Medical University, Salzburg, Austria.
- 2Department of Plastic Surgery, Community Hospital Feldkirch, Feldkirch, Austria.
- 3Department of Ophthalmology and Optometry, Paracelsus Medical University Salzburg, Salzburg, Austria.
- 4Research Program Experimental Ophthalmology & Glaucoma Research, Paracelsus Medical University Salzburg, Austria.
Abstract
Background
Prepectoral implant-based breast reconstruction after nipple-sparing mastectomy or skin-sparing mastectomy has already shown several advantages. Synthetic meshes are often used as a supportive layer to achieve satisfying and stable results. We present our data using Serasynth Mesh BR Pocket, a fully dissolvable, ready-to-use mesh pocket.Methods
Between December 2021 and August 2023, a single-center retrospective study evaluated 53 breast reconstructions (43 patients) for short-term complications. Complications were classified as major (requiring revision surgery) or minor (managed conservatively). All patients underwent nipple-sparing mastectomy or skin-sparing mastectomy followed by direct-to-implant or direct-to-expander reconstruction using Serasynth Mesh BR Pocket. The minimum follow-up was 4 weeks.Results
Of 53 breasts, 44 (83%) required no further surgical intervention, with a mean follow-up of 10 months (range 1-20, mo). Major complications occurred in 9 breasts (17%), and minor complications occurred in 13 (24.5%). Implant loss (13.2%) was primarily due to necrosis (7.5%). A higher body mass index (≥27 kg/m²) and axillary lymph node excision were associated with an increased risk of complications. Notably, 41.9% of patients received adjuvant radiotherapy.Conclusions
Serasynth Mesh BR Pocket demonstrates a favorable safety profile in prepectoral breast reconstruction, even in a high-risk cohort with substantial radiotherapy exposure. Outcomes are comparable to those of other synthetic meshes, with the added benefit of full resorbability. Careful patient selection, considering body mass index, soft-tissue quality, and lymph node dissection, is essential to optimize results.
Related
- Long-term implant integrity and complications after risk-reducing mastectomy with immediate implant reconstruction: a retrospective cohort study with prospective ultrasound follow-up at a Swedish university hospital
- Comparison of surgical outcomes, safety, and cosmetic satisfaction between immediate implant-based and transverse rectus abdominis myocutaneous (TRAM) flap breast reconstruction following total mastectomy: a retrospective cohort study
- Peri-areolar dermal reinforcement to prevent prosthetic-related complications in prepectoral reconstruction with a compromised nipple-areola complex: a surgical technique
- Short-term implant survivorship and failure modes of the LPS™ system in distal femoral reconstruction: A multicentre retrospective study
- No superiority of double drains over single drainage after tissue expander–based breast reconstruction: A systematic review and meta-analysis
BibTeX
@article{wimmer2026serasynth,
title = {{Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.}},
author = {Florian Wimmer and Alexander Panzirsch and Wolfgang Hitzl and Gabriel Djedovic},
journal = {Plastic and reconstructive surgery. Global open},
year = {2026},
month = oct,
doi = {10.1097/gox.0000000000008178},
url = {https://europepmc.org/article/MED/42903288},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Serasynth Mesh BR Pocket in Prepectoral Direct-to-implant and Tissue-expander Breast Reconstruction: A Retrospective Single-center Analysis.
AU - Florian Wimmer
AU - Alexander Panzirsch
AU - Wolfgang Hitzl
AU - Gabriel Djedovic
PY - 2026
DA - 2026/10/20
JO - Plastic and reconstructive surgery. Global open
DO - 10.1097/gox.0000000000008178
UR - https://europepmc.org/article/MED/42903288
AB - Background Prepectoral implant-based breast reconstruction after nipple-sparing mastectomy or skin-sparing mastectomy has already shown several advantages. Synthetic meshes are often used as a supportive layer to achieve satisfying and stable results. We present our data using Serasynth Mesh BR Pocket, a fully dissolvable, ready-to-use mesh pocket.Methods Between December 2021 and August 2023, a single-center retrospective study evaluated 53 breast reconstructions (43 patients) for short-term complications. Complications were classified as major (requiring revision surgery) or minor (managed conservatively). All patients underwent nipple-sparing mastectomy or skin-sparing mastectomy followed by direct-to-implant or direct-to-expander reconstruction using Serasynth Mesh BR Pocket. The minimum follow-up was 4 weeks.Results Of 53 breasts, 44 (83%) required no further surgical intervention, with a mean follow-up of 10 months (range 1-20, mo). Major complications occurred in 9 breasts (17%), and minor complications occurred in 13 (24.5%). Implant loss (13.2%) was primarily due to necrosis (7.5%). A higher body mass index (≥27 kg/m²) and axillary lymph node excision were associated with an increased risk of complications. Notably, 41.9% of patients received adjuvant radiotherapy.Conclusions Serasynth Mesh BR Pocket demonstrates a favorable safety profile in prepectoral breast reconstruction, even in a high-risk cohort with substantial radiotherapy exposure. Outcomes are comparable to those of other synthetic meshes, with the added benefit of full resorbability. Careful patient selection, considering body mass index, soft-tissue quality, and lymph node dissection, is essential to optimize results.
SN - 2169-7574
ER -