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Peer-reviewedCC BY-NC-NDInternal Medicine

A Case of Synchronous Subcarinal Lymph Node Metastasis from Double Primary Cancers with Small Cell Lung Cancer and Prostate Cancer

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Abstract

A 78-year-old man presented with a history of weight loss. A systemic examination revealed lung and prostate cancers. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of a subcarinal lymph node revealed combined small-cell and non-small-cell carcinoma. Prostate-specific antigen (PSA) staining was performed to exclude distant metastases from prostate cancer. A positive result confirmed synchronous lymph node metastasis from a double cancer of small cell lung cancer and prostate cancer. When biopsies reveal multiple histological types, the possibility of metastasis from other cancer types should be carefully evaluated.

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BibTeX
@article{satoh2026case,
  title = {{A Case of Synchronous Subcarinal Lymph Node Metastasis from Double Primary Cancers with Small Cell Lung Cancer and Prostate Cancer}},
  author = {Tsukasa Satoh and Ryota Saito and Toshio Oyama and Ryosuke Tajiri and Kazuyuki Miyata and Hinata Matsuda and Takuya Inoue and Kouki Hata and Makoto Kawaguchi and Hiroaki Kobayashi and Toshiharu Tsutsui and Yumiko Kakizaki and Yoshihiro Miyashita},
  journal = {Internal Medicine},
  year = {2026},
  month = jul,
  doi = {10.2169/internalmedicine.6883-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6883-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - A Case of Synchronous Subcarinal Lymph Node Metastasis from Double Primary Cancers with Small Cell Lung Cancer and Prostate Cancer
AU  - Tsukasa Satoh
AU  - Ryota Saito
AU  - Toshio Oyama
AU  - Ryosuke Tajiri
AU  - Kazuyuki Miyata
AU  - Hinata Matsuda
AU  - Takuya Inoue
AU  - Kouki Hata
AU  - Makoto Kawaguchi
AU  - Hiroaki Kobayashi
AU  - Toshiharu Tsutsui
AU  - Yumiko Kakizaki
AU  - Yoshihiro Miyashita
PY  - 2026
DA  - 2026/07/11
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6883-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/advpub/0/advpub_6883-25/_article
AB  - A 78-year-old man presented with a history of weight loss. A systemic examination revealed lung and prostate cancers. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of a subcarinal lymph node revealed combined small-cell and non-small-cell carcinoma. Prostate-specific antigen (PSA) staining was performed to exclude distant metastases from prostate cancer. A positive result confirmed synchronous lymph node metastasis from a double cancer of small cell lung cancer and prostate cancer. When biopsies reveal multiple histological types, the possibility of metastasis from other cancer types should be carefully evaluated.
SN  - 1349-7235
SN  - 0918-2918
ER  -