Evaluating the reliability, quality, and readability of AI-generated patient education on hallux valgus: a comparative study of large language models
7 affiliations
- 1Department of Orthopaedics and Traumatology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, 34147 Turkey
- 2Division of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Istanbul Okan University, Istanbul, 34959 Turkey
- 3Department of Physiotherapy and Rehabilitation, Institute of Graduate Education, Istinye University, Istanbul, 34010 Turkey
- 4Department of Orthopaedics and Traumatology, Sultan Abdülhamid Han Training and Research Hospital, Istanbul, 34668 Turkey
- 5Department of Orthopaedics and Traumatology, Beylikduzu State Hospital, Istanbul, 34500 Turkey
- 6Vocational School of Health Services, Department of Orthopedic Prosthetics and Orthotics, Acibadem Mehmet Ali Aydinlar University, Istanbul, 34638 Turkey
- 7Department of Orthopaedics and Traumatology, Acibadem University Atakent Hospital, Istanbul, 34303 Turkey
Abstract
Background: Patients with hallux valgus increasingly seek health information through consumer-facing artificial intelligence (AI)–driven patient education tools, particularly large language model–based conversational agents. Although these tools offer rapid and accessible responses, concerns remain regarding the reliability, usefulness, overall quality, and readability of AI-generated patient education materials. Evidence specifically evaluating AI-generated patient education for hallux valgus, a condition strongly influenced by patient expectations and treatment preferences, remains limited.
Methods: This cross-sectional comparative study evaluated the performance of three large language models—ChatGPT-4o, Gemini-2.5-Flash, and DeepSeek-V3—in responding to 20 patient-centered questions related to hallux valgus. Questions were developed using AI-assisted question generation and publicly available Google Trends search patterns and categorized into four clinical domains. AI-generated responses were anonymized and independently assessed by three orthopaedic surgeons for reliability, usefulness, and overall quality using 7-point Likert-based reliability and usefulness scales and the Global Quality Scale (GQS). Readability was analyzed using six standardized indices. Inter-rater agreement and between-model comparisons were statistically evaluated.
Results: Gemini-2.5-Flash demonstrated modestly higher overall reliability, particularly in questions related to etiology and clinical presentation. DeepSeek-V3 achieved higher usefulness scores in the long-term outcomes and quality-of-life domain and produced significantly more readable content, as reflected by higher Flesch Reading Ease scores and lower grade-level indices. In contrast, Gemini-2.5-Flash generated linguistically more complex responses requiring higher educational levels for comprehension. Overall usefulness and global quality scores did not differ significantly among models. Qualitative review also identified occasional examples of oversimplified or potentially misleading information. Despite these differences, several readability metrics exceeded recommended patient health-literacy thresholds.
Conclusions: Contemporary AI-based conversational agents can provide patient-oriented information regarding hallux valgus with variable reliability and readability characteristics, although statistically significant differences were observed across models. A trade-off between factual accuracy and linguistic accessibility was observed. AI tools should therefore be regarded as adjuncts to, rather than replacements for, clinician-led patient education. Awareness of AI limitations and appropriate clinical guidance remain essential to ensure safe, accurate, and patient-centered information delivery.
Clinical trial number: Not applicable.
Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12911-026-03722-8.
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BibTeX
@article{koluman2026evaluating,
title = {{Evaluating the reliability, quality, and readability of AI-generated patient education on hallux valgus: a comparative study of large language models}},
author = {Ali Can Koluman and Ebru Aloglu Ciftci and Mehmet Utku Ciftci and Başar Burak Cakmur and Nezih Ziroglu},
journal = {BMC Medical Informatics and Decision Making},
year = {2026},
month = jul,
doi = {10.1186/s12911-026-03722-8},
url = {https://doi.org/10.1186/s12911-026-03722-8},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Evaluating the reliability, quality, and readability of AI-generated patient education on hallux valgus: a comparative study of large language models
AU - Ali Can Koluman
AU - Ebru Aloglu Ciftci
AU - Mehmet Utku Ciftci
AU - Başar Burak Cakmur
AU - Nezih Ziroglu
PY - 2026
DA - 2026/07/01
JO - BMC Medical Informatics and Decision Making
DO - 10.1186/s12911-026-03722-8
UR - https://doi.org/10.1186/s12911-026-03722-8
AB - Background: Patients with hallux valgus increasingly seek health information through consumer-facing artificial intelligence (AI)–driven patient education tools, particularly large language model–based conversational agents. Although these tools offer rapid and accessible responses, concerns remain regarding the reliability, usefulness, overall quality, and readability of AI-generated patient education materials. Evidence specifically evaluating AI-generated patient education for hallux valgus, a condition strongly influenced by patient expectations and treatment preferences, remains limited. Methods: This cross-sectional comparative study evaluated the performance of three large language models—ChatGPT-4o, Gemini-2.5-Flash, and DeepSeek-V3—in responding to 20 patient-centered questions related to hallux valgus. Questions were developed using AI-assisted question generation and publicly available Google Trends search patterns and categorized into four clinical domains. AI-generated responses were anonymized and independently assessed by three orthopaedic surgeons for reliability, usefulness, and overall quality using 7-point Likert-based reliability and usefulness scales and the Global Quality Scale (GQS). Readability was analyzed using six standardized indices. Inter-rater agreement and between-model comparisons were statistically evaluated. Results: Gemini-2.5-Flash demonstrated modestly higher overall reliability, particularly in questions related to etiology and clinical presentation. DeepSeek-V3 achieved higher usefulness scores in the long-term outcomes and quality-of-life domain and produced significantly more readable content, as reflected by higher Flesch Reading Ease scores and lower grade-level indices. In contrast, Gemini-2.5-Flash generated linguistically more complex responses requiring higher educational levels for comprehension. Overall usefulness and global quality scores did not differ significantly among models. Qualitative review also identified occasional examples of oversimplified or potentially misleading information. Despite these differences, several readability metrics exceeded recommended patient health-literacy thresholds. Conclusions: Contemporary AI-based conversational agents can provide patient-oriented information regarding hallux valgus with variable reliability and readability characteristics, although statistically significant differences were observed across models. A trade-off between factual accuracy and linguistic accessibility was observed. AI tools should therefore be regarded as adjuncts to, rather than replacements for, clinician-led patient education. Awareness of AI limitations and appropriate clinical guidance remain essential to ensure safe, accurate, and patient-centered information delivery. Clinical trial number: Not applicable. Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1186/s12911-026-03722-8.
SN - 1472-6947
ER -