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Peer-reviewedCC BYSAGE Open Medical Case Reports

Histiocytoid sweet syndrome in a patient with monoclonal gammopathy and skin of color: A case report

  • Nathalie Daccache
  • Samantha Bizimungu MD
  • Victor Estenssoro-Alvarez MD
  • Annie Bélisle MD
  • Dominique Friedmann MD
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Abstract

Sweet syndrome (SS) is an uncommon neutrophilic dermatosis associated with a number of systemic conditions including infections, inflammatory bowel disease and hematologic malignancy. Histiocytoid Sweet syndrome is a histologic variant of SS in which the dermal infiltrate contains histiocyte-like immature myeloid cells. This variant may confer an increased risk of association with hematologic malignancies. In patients with darker skin types, SS may be misdiagnosed, in part due to a lack of representative images in the literature. Misdiagnosis may prevent patients from obtaining the necessary workup for underlying conditions. Herein we present a case of a 41-year-old woman with Fitzpatrick type VI skin diagnosed with histiocytoid sweet syndrome.

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Cite

BibTeXRIS
BibTeX
@article{daccache2026histiocytoid,
  title = {{Histiocytoid sweet syndrome in a patient with monoclonal gammopathy and skin of color: A case report}},
  author = {Nathalie Daccache and Samantha Bizimungu MD and Victor Estenssoro-Alvarez MD and Annie Bélisle MD and Dominique Friedmann MD},
  journal = {SAGE Open Medical Case Reports},
  year = {2026},
  month = nov,
  doi = {10.1177/2050313x261505387},
  url = {https://doi.org/10.1177/2050313x261505387},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Histiocytoid sweet syndrome in a patient with monoclonal gammopathy and skin of color: A case report
AU  - Nathalie Daccache
AU  - Samantha Bizimungu MD
AU  - Victor Estenssoro-Alvarez MD
AU  - Annie Bélisle MD
AU  - Dominique Friedmann MD
PY  - 2026
DA  - 2026/11/04
JO  - SAGE Open Medical Case Reports
DO  - 10.1177/2050313x261505387
UR  - https://doi.org/10.1177/2050313x261505387
AB  - Sweet syndrome (SS) is an uncommon neutrophilic dermatosis associated with a number of systemic conditions including infections, inflammatory bowel disease and hematologic malignancy. Histiocytoid Sweet syndrome is a histologic variant of SS in which the dermal infiltrate contains histiocyte-like immature myeloid cells. This variant may confer an increased risk of association with hematologic malignancies. In patients with darker skin types, SS may be misdiagnosed, in part due to a lack of representative images in the literature. Misdiagnosis may prevent patients from obtaining the necessary workup for underlying conditions. Herein we present a case of a 41-year-old woman with Fitzpatrick type VI skin diagnosed with histiocytoid sweet syndrome.
SN  - 2050-313X
ER  -