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Peer-reviewedCC BY-NC-ND 4.0Journal of Medical Case Reports

Cutaneous metastasis in laryngeal squamous cell carcinoma: a case report and review of the literature

  • Xue Zhang1,2,3
  • Hong Lv1
  • Yuhao Zou1
  • Houyu Zhao1
  • Jifeng Liu1
  1. 1Department of Otolaryngology Head and Neck Surgery, West China Hospital, Sichuan University, No. 37 Guoxuexiang, Chengdu, China
  2. 2Department of Otorhinolaryngolog Head and Neck Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000 Sichuan China
  3. 3Department of Otorhinolaryngology Head and Neck Surgery, Guizhou Medical University, No. 55 Yunyan Road Guiyang, Guiyang, 550004 Guizhou China
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Abstract

Background: Cutaneous metastasis from laryngeal squamous cell carcinoma (LSCC) is rare and is generally associated with advanced disease and poor prognosis. It often reflects aggressive tumor behavior and may occur in conjunction with systemic metastasis.

Case presentation: We report the case of an 83-year-old Han Chinese man diagnosed with supraglottic LSCC. Owing to his advanced age, the patient underwent surgical resection alone without adjuvant radiotherapy or chemotherapy. Four months after surgery, a solitary cutaneous metastatic lesion developed on the ipsilateral neck. The lesion was completely excised, and no local recurrence or additional distant metastases have been detected during follow-up to date.

Conclusions: This case highlights the importance of maintaining a high index of suspicion for cutaneous metastasis when new skin lesions arise during follow-up of patients with laryngeal carcinoma. Early recognition and prompt management may facilitate timely intervention. In addition, this report adds to the existing literature by illustrating an uncommon metastatic presentation of LSCC and its clinical course.

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Cite

BibTeXRIS
BibTeX
@article{zhang2026cutaneous,
  title = {{Cutaneous metastasis in laryngeal squamous cell carcinoma: a case report and review of the literature}},
  author = {Xue Zhang and Hong Lv and Yuhao Zou and Houyu Zhao and Jifeng Liu},
  journal = {Journal of Medical Case Reports},
  year = {2026},
  month = aug,
  doi = {10.1186/s13256-026-06370-8},
  url = {https://doi.org/10.1186/s13256-026-06370-8},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Cutaneous metastasis in laryngeal squamous cell carcinoma: a case report and review of the literature
AU  - Xue Zhang
AU  - Hong Lv
AU  - Yuhao Zou
AU  - Houyu Zhao
AU  - Jifeng Liu
PY  - 2026
DA  - 2026/08/06
JO  - Journal of Medical Case Reports
DO  - 10.1186/s13256-026-06370-8
UR  - https://doi.org/10.1186/s13256-026-06370-8
AB  - Background: Cutaneous metastasis from laryngeal squamous cell carcinoma (LSCC) is rare and is generally associated with advanced disease and poor prognosis. It often reflects aggressive tumor behavior and may occur in conjunction with systemic metastasis.  Case presentation: We report the case of an 83-year-old Han Chinese man diagnosed with supraglottic LSCC. Owing to his advanced age, the patient underwent surgical resection alone without adjuvant radiotherapy or chemotherapy. Four months after surgery, a solitary cutaneous metastatic lesion developed on the ipsilateral neck. The lesion was completely excised, and no local recurrence or additional distant metastases have been detected during follow-up to date.  Conclusions: This case highlights the importance of maintaining a high index of suspicion for cutaneous metastasis when new skin lesions arise during follow-up of patients with laryngeal carcinoma. Early recognition and prompt management may facilitate timely intervention. In addition, this report adds to the existing literature by illustrating an uncommon metastatic presentation of LSCC and its clinical course.
SN  - 1752-1947
ER  -