Simultaneous pigmented villonodular synovitis and synovial chondromatosis of the knee joint: case report
- 1Department of Orthopaedic, Chongqing Songshan General Hospital, Chongqing, China
Abstract
Background:: Pigmented villonodular synovitis (PVNS) and synovial chondromatosis (SC) are rare joint diseases. Their coexistence within the same joint is exceedingly rare, and understanding such overlapping joint pathologies is crucial for improving diagnosis and treatment strategies.
Materials and methods:: This case has been reported in accordance with the SCARE criteria. A patient presenting with knee pain and swelling underwent arthroscopic examination. Arthroscopic findings suggested the presence of both PVNS and SC. To confirm the diagnosis, post-operative histopathological analysis was performed on synovial tissue samples obtained during arthroscopy.
Results:: Histopathological examination confirmed the simultaneous presence of PVNS and SC in the knee joint. To our knowledge, this is the first reported case of these two conditions coexisting within an adult knee joint. Arthroscopic examination provided key visual findings that guided the collection of samples, while histopathology validated the overlapping diagnoses.
Conclusion:: We report a detailed case of simultaneous PVNS and SC in an adult knee joint. The affected synovium and loose bodies were removed arthroscopically, although long-term follow-up is still required. In summary, this case provides valuable clinical insight into a rare presentation, while the underlying cellular and molecular mechanisms warrant further investigation.
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BibTeX
@article{zhou2026simultaneous,
title = {{Simultaneous pigmented villonodular synovitis and synovial chondromatosis of the knee joint: case report}},
author = {Ping Zhou and Aimin Wang},
journal = {International Journal of Surgery Case Reports},
year = {2026},
month = sep,
doi = {10.1097/rc9.0000000000000995},
url = {https://doi.org/10.1097/rc9.0000000000000995},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - JOUR
TI - Simultaneous pigmented villonodular synovitis and synovial chondromatosis of the knee joint: case report
AU - Ping Zhou
AU - Aimin Wang
PY - 2026
DA - 2026/09/23
JO - International Journal of Surgery Case Reports
DO - 10.1097/rc9.0000000000000995
UR - https://doi.org/10.1097/rc9.0000000000000995
AB - Background:: Pigmented villonodular synovitis (PVNS) and synovial chondromatosis (SC) are rare joint diseases. Their coexistence within the same joint is exceedingly rare, and understanding such overlapping joint pathologies is crucial for improving diagnosis and treatment strategies. Materials and methods:: This case has been reported in accordance with the SCARE criteria. A patient presenting with knee pain and swelling underwent arthroscopic examination. Arthroscopic findings suggested the presence of both PVNS and SC. To confirm the diagnosis, post-operative histopathological analysis was performed on synovial tissue samples obtained during arthroscopy. Results:: Histopathological examination confirmed the simultaneous presence of PVNS and SC in the knee joint. To our knowledge, this is the first reported case of these two conditions coexisting within an adult knee joint. Arthroscopic examination provided key visual findings that guided the collection of samples, while histopathology validated the overlapping diagnoses. Conclusion:: We report a detailed case of simultaneous PVNS and SC in an adult knee joint. The affected synovium and loose bodies were removed arthroscopically, although long-term follow-up is still required. In summary, this case provides valuable clinical insight into a rare presentation, while the underlying cellular and molecular mechanisms warrant further investigation.
SN - 2210-2612
ER -