Disease-specific quality of life and associated health outcomes among children with diabetes in Khartoum state, sudan: a cross-sectional study
- 1College of Medicine, Gulf Medical University
- 2National University
- 3Department of Community Medicine, University of Khartoum. AL
Abstract
Diabetes mellitus is a prevalent non-communicable disease that adversely affects multiple dimensions of quality of life in children and adolescents. This study aimed to assess disease-specific quality of life (Ds-QoL) among children with diabetes and to identify associated demographic and clinical factors. A cross-sectional study was conducted in 2020–2021 in major paediatric diabetes clinics in Khartoum, Sudan. A total of 138 children with diabetes and their parents were recruited using systematic random sampling. Disease-specific quality of life was assessed using the Paediatric Quality of Life Inventory (PedsQL) 3.0 Diabetes Module. Demographic, clinical, and care-related variables were analysed using bivariate tests and multivariable models, including generalized linear modelling. Participants had a mean age of 11.1 ± 3.6 years; 64% were female, and 74.6% resided in urban areas. Type 1 diabetes was predominant (92.8%), and glycaemic control was poor in 92.3% of participants (mean HbA1c = 9.38 ± 2.59%). Children reported higher overall Ds-QoL scores than 2 parents (75.35 ± 12.02 vs. 70.82 ± 15.94). Significant child–parent differences were observed in diabetes symptoms (p = 0.003) and worry (p < 0.001), while communication scores were comparable. Increasing age was associated with greater treatment burden (r = − 0.332, p < 0.001) and diabetes-related worry (r = − 0.254, p = 0.004). Sociodemographic variables were not significantly associated with overall Ds-QoL. Hospitalization, hypoglycaemia, and diabetic ketoacidosis were associated with lower child-reported Ds-QoL, whereas regular follow-up was associated with higher Ds-QoL. In multivariable analysis, hypoglycaemia (B = − 4.97, p = 0.027) and diabetic ketoacidosis (B = − 6.48, p = 0.012) independently predicted poorer child-reported Ds-QoL. At the same time, glycaemic control was the only independent predictor of parent-reported Ds-QoL (p = 0.001). Diabetes-specific quality of life in children is primarily influenced by clinical stability and acute complications rather than sociodemographic factors. Integrating child and parent perspectives and strengthening follow-up and metabolic control may improve quality-of-life outcomes.
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BibTeX
@article{hajomer2026diseasespecific,
title = {{Disease-specific quality of life and associated health outcomes among children with diabetes in Khartoum state, sudan: a cross-sectional study}},
author = {Hiba Hajomer and Osama Elkhidir and Kamil Shaaban and Qurashi Ali and Marwa Mady and Shatha AlSharbatti and Mayssah El Nayal},
journal = {Scientific Reports},
year = {2026},
month = jul,
doi = {10.1038/s41598-026-62496-1},
url = {https://doi.org/10.1038/s41598-026-62496-1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Disease-specific quality of life and associated health outcomes among children with diabetes in Khartoum state, sudan: a cross-sectional study
AU - Hiba Hajomer
AU - Osama Elkhidir
AU - Kamil Shaaban
AU - Qurashi Ali
AU - Marwa Mady
AU - Shatha AlSharbatti
AU - Mayssah El Nayal
PY - 2026
DA - 2026/07/01
JO - Scientific Reports
DO - 10.1038/s41598-026-62496-1
UR - https://doi.org/10.1038/s41598-026-62496-1
AB - Diabetes mellitus is a prevalent non-communicable disease that adversely affects multiple dimensions of quality of life in children and adolescents. This study aimed to assess disease-specific quality of life (Ds-QoL) among children with diabetes and to identify associated demographic and clinical factors. A cross-sectional study was conducted in 2020–2021 in major paediatric diabetes clinics in Khartoum, Sudan. A total of 138 children with diabetes and their parents were recruited using systematic random sampling. Disease-specific quality of life was assessed using the Paediatric Quality of Life Inventory (PedsQL) 3.0 Diabetes Module. Demographic, clinical, and care-related variables were analysed using bivariate tests and multivariable models, including generalized linear modelling. Participants had a mean age of 11.1 ± 3.6 years; 64% were female, and 74.6% resided in urban areas. Type 1 diabetes was predominant (92.8%), and glycaemic control was poor in 92.3% of participants (mean HbA1c = 9.38 ± 2.59%). Children reported higher overall Ds-QoL scores than 2 parents (75.35 ± 12.02 vs. 70.82 ± 15.94). Significant child–parent differences were observed in diabetes symptoms (p = 0.003) and worry (p < 0.001), while communication scores were comparable. Increasing age was associated with greater treatment burden (r = − 0.332, p < 0.001) and diabetes-related worry (r = − 0.254, p = 0.004). Sociodemographic variables were not significantly associated with overall Ds-QoL. Hospitalization, hypoglycaemia, and diabetic ketoacidosis were associated with lower child-reported Ds-QoL, whereas regular follow-up was associated with higher Ds-QoL. In multivariable analysis, hypoglycaemia (B = − 4.97, p = 0.027) and diabetic ketoacidosis (B = − 6.48, p = 0.012) independently predicted poorer child-reported Ds-QoL. At the same time, glycaemic control was the only independent predictor of parent-reported Ds-QoL (p = 0.001). Diabetes-specific quality of life in children is primarily influenced by clinical stability and acute complications rather than sociodemographic factors. Integrating child and parent perspectives and strengthening follow-up and metabolic control may improve quality-of-life outcomes.
SN - 2045-2322
ER -