Optical coherence tomography angiography quantitative analysis and 10-year cardiovascular disease risk in the general population
Abstract
PURPOSE: The aim of our study was to analyze the association between different cardiovascular risk scores and swept-source optical coherence tomography angiography (SS-OCTA) quantitative parameters in the general population. MATERIALS AND METHODS: We performed a retrospective study. This study enrolled 111 eyes of 111 healthy patients. OCTA quantitative parameters (vessel density [VD] and foveal avascular zone area of superficial capillary plexus [SCP], deep capillary plexus [DCP], total capillary plexus, and choriocapillaris [CC]) of the OCTA cube of 4.5 mm × 4.5 mm were recorded. RESULTS: A decrease of parafoveal and total VD in TCP was demonstrated in patients with higher cardiovascular risk (P < 0.05). Conversely, no differences were demonstrated in VD at SCP, DCP, and CC (P > 0.05). Correlation analysis showed a significant, although poor, negative correlation between parafoveal and total VD at SCP and TCP and 10-year cardiovascular disease (CVD) risk (P < 0.05 and r < 0.500). CONCLUSION: When normative data are available, OCTA quantitative analysis might be used as a main tool for the primary prevention of CVD. Nevertheless, further prospective studies are needed to confirm this hypothesis.
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BibTeX
@article{remolisargues2026optical,
title = {{Optical coherence tomography angiography quantitative analysis and 10-year cardiovascular disease risk in the general population}},
author = {Lidia Remolí-Sargues and Clara Monferrer-Adsuara and Belén López-Salvador and Enrique López-Sánchez and Ester Francés-Muñoz and Verónica Castro-Navarro},
journal = {Taiwan Journal of Ophthalmology},
year = {2026},
month = jul,
doi = {10.4103/tjo.tjo-d-25-00055},
url = {https://doi.org/10.4103/tjo.tjo-d-25-00055},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Optical coherence tomography angiography quantitative analysis and 10-year cardiovascular disease risk in the general population
AU - Lidia Remolí-Sargues
AU - Clara Monferrer-Adsuara
AU - Belén López-Salvador
AU - Enrique López-Sánchez
AU - Ester Francés-Muñoz
AU - Verónica Castro-Navarro
PY - 2026
DA - 2026/07/01
JO - Taiwan Journal of Ophthalmology
DO - 10.4103/tjo.tjo-d-25-00055
UR - https://doi.org/10.4103/tjo.tjo-d-25-00055
AB - PURPOSE: The aim of our study was to analyze the association between different cardiovascular risk scores and swept-source optical coherence tomography angiography (SS-OCTA) quantitative parameters in the general population. MATERIALS AND METHODS: We performed a retrospective study. This study enrolled 111 eyes of 111 healthy patients. OCTA quantitative parameters (vessel density [VD] and foveal avascular zone area of superficial capillary plexus [SCP], deep capillary plexus [DCP], total capillary plexus, and choriocapillaris [CC]) of the OCTA cube of 4.5 mm × 4.5 mm were recorded. RESULTS: A decrease of parafoveal and total VD in TCP was demonstrated in patients with higher cardiovascular risk (P < 0.05). Conversely, no differences were demonstrated in VD at SCP, DCP, and CC (P > 0.05). Correlation analysis showed a significant, although poor, negative correlation between parafoveal and total VD at SCP and TCP and 10-year cardiovascular disease (CVD) risk (P < 0.05 and r < 0.500). CONCLUSION: When normative data are available, OCTA quantitative analysis might be used as a main tool for the primary prevention of CVD. Nevertheless, further prospective studies are needed to confirm this hypothesis.
SN - 2211-5056
SN - 2211-5072
ER -