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Peer-reviewedCC BYACG case reports journal

Kaposi Sarcoma of the Ampulla of Vater and AIDS Cholangiopathy: A Rare Biliary Presentation

  • Jayasree Rajapandian1
  • Choudhary Ahmed Hasan Maqbool1
  • Yousif Elmofti1
  1. 1Heersink School of Medicine, Montgomery Regional Campus, University of Alabama at Birmingham, Montgomery, AL
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Abstract

Biliary manifestations in advanced acquired immunodeficiency syndrome (AIDS) present unique diagnostic challenges. We present a case of Kaposi sarcoma of the ampulla of Vater with AIDS cholangiopathy in a 25-year-old man. He presented with watery nonbloody diarrhea and loss of weight for 2 months with a cholestatic liver pattern. Magnetic resonance cholangiopancreatography showed hepatic lesions possibly Kaposi sarcoma and irregular bile and pancreatic ducts with a suspected stricture at the ampulla consistent with AIDS cholangiopathy. Endoscopic retrograde cholangiopancreatography confirmed a vascular, umbilicated lesion in the ampulla of Vater, which proved biliary stenting difficult. This case highlights the diagnostic complexity of these rare presentations of HIV.

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Cite

BibTeXRIS
BibTeX
@article{rajapandian2026kaposi,
  title = {{Kaposi Sarcoma of the Ampulla of Vater and AIDS Cholangiopathy: A Rare Biliary Presentation}},
  author = {Jayasree Rajapandian and Choudhary Ahmed Hasan Maqbool and Yousif Elmofti},
  journal = {ACG case reports journal},
  year = {2026},
  month = oct,
  doi = {10.14309/crj.0000000000002325},
  url = {https://europepmc.org/article/PMC/PMC13722500},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Kaposi Sarcoma of the Ampulla of Vater and AIDS Cholangiopathy: A Rare Biliary Presentation
AU  - Jayasree Rajapandian
AU  - Choudhary Ahmed Hasan Maqbool
AU  - Yousif Elmofti
PY  - 2026
DA  - 2026/10/30
JO  - ACG case reports journal
DO  - 10.14309/crj.0000000000002325
UR  - https://europepmc.org/article/PMC/PMC13722500
AB  - Biliary manifestations in advanced acquired immunodeficiency syndrome (AIDS) present unique diagnostic challenges. We present a case of Kaposi sarcoma of the ampulla of Vater with AIDS cholangiopathy in a 25-year-old man. He presented with watery nonbloody diarrhea and loss of weight for 2 months with a cholestatic liver pattern. Magnetic resonance cholangiopancreatography showed hepatic lesions possibly Kaposi sarcoma and irregular bile and pancreatic ducts with a suspected stricture at the ampulla consistent with AIDS cholangiopathy. Endoscopic retrograde cholangiopancreatography confirmed a vascular, umbilicated lesion in the ampulla of Vater, which proved biliary stenting difficult. This case highlights the diagnostic complexity of these rare presentations of HIV.
SN  - 2326-3253
ER  -