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Peer-reviewedCC BY-NC-NDClinical case reports

Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain

  1. 1Department of Internal Medicine UCI Medical Center Orange California USA
  2. 2Department of Rheumatology UCI Medical Center Orange California USA
  3. 3Tibor Rubin VA Medical Center Long Beach California USA

Abstract

We describe a 51‐year‐old male presenting with bilateral calf pain and found to have rapidly progressing pulmonary‐renal syndrome due to GPA vasculitis, despite completing an empiric course of steroids for a gout flare. This case underscores the heterogeneous nature of GPA and the importance of early strong immunosuppressive therapy.

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BibTeX
@article{allison2026rapidly,
  title = {{Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain}},
  author = {Lily Gupta (Allison) and Yingxue Wang and Eugenia Chen},
  journal = {Clinical case reports},
  year = {2026},
  month = nov,
  doi = {10.1002/ccr3.73819},
  url = {https://europepmc.org/article/PMC/PMC13728996},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Rapidly Progressing Interstitial Fibrosis and Glomerulonephritis due to Granulomatosis With Polyangiitis Presenting With Calf Pain
AU  - Lily Gupta (Allison)
AU  - Yingxue Wang
AU  - Eugenia Chen
PY  - 2026
DA  - 2026/11/01
JO  - Clinical case reports
DO  - 10.1002/ccr3.73819
UR  - https://europepmc.org/article/PMC/PMC13728996
AB  - We describe a 51‐year‐old male presenting with bilateral calf pain and found to have rapidly progressing pulmonary‐renal syndrome due to GPA vasculitis, despite completing an empiric course of steroids for a gout flare. This case underscores the heterogeneous nature of GPA and the importance of early strong immunosuppressive therapy.
SN  - 2050-0904
ER  -