Skip to content
DraconiticResearch
Search Sources API
197,787 studies31 sourcesUpdated 20 min ago
Peer-reviewedCC BYClinical and translational radiation oncology

Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.

  • Einar Björgvinsson1,2
  • Aeneas Kolev3,4
  • Eva Onjukka2,5
  • Mattias Hedman2,6
  • Åsa Carlsson Tedgren2,5
  • Lars Södergren5
  • Signe Friesland1,2
  • Gregori Margolin3,4
  • Lars-Olaf Cardell3,4
  • Michael Gubanski2,6
6 affiliations
  1. 1Department of Head and Neck Oncology, Karolinska University Hospital, 17164 Stockholm, Sweden.
  2. 2Department of Oncology-Pathology, Karolinska Institution, 171 77 Stockholm, Sweden.
  3. 3Department of Head and Neck Surgery, Karolinska University Hospital, 17164 Stockholm, Sweden.
  4. 4Department of Science, Intervention and Technique, Karolinska Institution, 141 52 Stockholm, Sweden.
  5. 5Department of Nuclear Medicine, Karolinska University Hospital, 17164 Stockholm, Sweden.
  6. 6Department of Radiation Therapy, Karolinska University Hospital, 17164 Stockholm, Sweden.
Read full textPDFDOICite

Abstract

•SLNB identified lymphatic drainage beyond standard elective volumes in nearly half of OTSCC patients.•SLNB may guide individualized postoperative radiotherapy, including omission of contralateral neck irradiation in selected patients.•Adapted plans significantly reduced estimated NTCPs for xerostomia and dysphagia.•SLNB may support individualized de-escalation and optimization of elective neck irradiation in OTSCC.

Related

  1. Postoperative radiotherapy after tracheal reconstruction with cryopreserved aortic allograft for adenoid cystic carcinoma
    Arnaud Beddok, Nicolas Venissac, Marine Boulesteix +10
    Practical Radiation Oncology: An official journal of the American Society for Radiation OncologyPeer-reviewedLicence not statedFull textGeneral biologyGeneral medicineHAL
  2. Safety of concurrent immune checkpoint inhibitor therapy during postoperative radiotherapy for triple-negative breast cancer: A preliminary retrospective analysis
    Gai Liang, Qu Zhang, Mengting Yuan +2
    Oncology LettersPeer-reviewedLicence not statedFull textOncologyPMC
  3. Overtreatment risk of postoperative radiotherapy in FIGO I–III cervical small cell neuroendocrine carcinoma: a population-based study
    Dun-Chang Mo, Jian-Feng Huang, Peng-Hui Luo +5
    Frontiers in EndocrinologyPeer-reviewedCC BY 4.0Endocrinology & metabolismCrossref
  4. The crucial question: does adjuvant radiotherapy confer a survival benefit in pN1 oral squamous cell carcinoma (OSCC)? - A retrospective analysis.
    Maximilian Richter, Aleksandra Tworek, Steffen Koerdt +5
    Oral and maxillofacial surgeryPeer-reviewedCC BYFull textGeneral medicineEurope PMC
  5. Retrospective Analysis of Efficacy and Toxicity of Low-Dose Weekly Cisplatin Concurrently with Radiotherapy for p16-Positive Oropharyngeal Squamous Cell Carcinoma
    Nitin Niranjan, Zulfiquer Otty, Abhishek Joshi +13
    CancersPeer-reviewedCC BY 4.0Full textOncologyCrossrefEurope PMC

Cite

BibTeXRIS
BibTeX
@article{bjorgvinsson2026sentinel,
  title = {{Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.}},
  author = {Einar Björgvinsson and Aeneas Kolev and Eva Onjukka and Mattias Hedman and Åsa Carlsson Tedgren and Lars Södergren and Signe Friesland and Gregori Margolin and Lars-Olaf Cardell and Michael Gubanski},
  journal = {Clinical and translational radiation oncology},
  year = {2026},
  month = oct,
  doi = {10.1016/j.ctro.2026.101306},
  url = {https://europepmc.org/article/MED/42927216},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.
AU  - Einar Björgvinsson
AU  - Aeneas Kolev
AU  - Eva Onjukka
AU  - Mattias Hedman
AU  - Åsa Carlsson Tedgren
AU  - Lars Södergren
AU  - Signe Friesland
AU  - Gregori Margolin
AU  - Lars-Olaf Cardell
AU  - Michael Gubanski
PY  - 2026
DA  - 2026/10/08
JO  - Clinical and translational radiation oncology
DO  - 10.1016/j.ctro.2026.101306
UR  - https://europepmc.org/article/MED/42927216
AB  - •SLNB identified lymphatic drainage beyond standard elective volumes in nearly half of OTSCC patients.•SLNB may guide individualized postoperative radiotherapy, including omission of contralateral neck irradiation in selected patients.•Adapted plans significantly reduced estimated NTCPs for xerostomia and dysphagia.•SLNB may support individualized de-escalation and optimization of elective neck irradiation in OTSCC.
SN  - 2405-6308
ER  -