Clinical Characteristics and Surgical Management of Calvarial Tumors: A Single-Center Retrospective Study
4 affiliations
- 1Department of Neurosurgery, İzmir City Hospital, Bayraklı, 35540 İzmir, Türkiye
- 2Department of Neurosurgery, İzmir Faculty of Medicine, University of Health Sciences, 35100 İzmir, Türkiye
- 3Department of Neurosurgery, Faculty of Medicine, Muğla Sıtkı Koçman University, 48000 Muğla, Türkiye
- 4Department of Endodontics, Faculty of Dentistry, Selçuk University, 42250 Konya, Türkiye
Abstract
Background/Objectives: Calvarial tumors form a heterogeneous group of benign and malignant lesions, and institutional series remain limited, particularly from Türkiye. This study aimed to describe the clinical, radiological, histopathological, and surgical features and histology-specific outcomes of calvarial tumors treated at a single neurosurgical center. Methods: We retrospectively reviewed 42 patients who underwent surgery for histopathologically confirmed tumors and tumor-like lesions of the cranial vault between 2019 and 2024. Clinical, imaging, histopathological, surgical, and follow-up data were analyzed. Results: The cohort comprised 24 men and 18 women (mean age 42.6 ± 15.3 years; range 7–78). A palpable mass was the most common complaint (64%), and the frontal bone was the most common site (38%). Lesions were benign in 25 patients (60%, including 6 with fibrous dysplasia) and malignant in 17 (40%); osteoma and metastasis were the leading diagnoses. Malignant tumors were larger and had a shorter symptom duration than benign lesions. Total resection was achieved in 36 patients (86%). During a mean follow-up of 32 months, recurrence occurred in 8% (95% CI 2–25%) of benign and 35% (95% CI 17–59%) of malignant tumors (p = 0.045); 8 recurrences occurred after total resection. Conclusions: In this surgical series, a short symptom duration, larger lesion size, and destructive CT features were associated with malignancy, although their diagnostic accuracy requires validation in larger cohorts. Recurrence was uncommon in those with benign lesions but occurred in about one-third of those with malignant tumors, which therefore require multidisciplinary management and close surveillance. Because recurrence also occurred after total resection, the extent of resection alone did not ensure local control.
Related
- OP–225 Beyond extra digits: clinical characteristics and surgical management of polydactyly
- Clinical Characteristics and Management of Pediatric Facial Wounds with Documented Infection or Delayed Presentation: A 25-Year Retrospective Case Series
- The Clinical Characteristics and Management of Dental-Related Foreign Body Accidents: A Retrospective Observational Study.
- Clinical characteristics, diagnostic challenges, and management of pulmonary actinomycosis: a 10-year retrospective cohort study
- Case Report: Catamenial pneumothorax: clinical characteristics, diagnosis, and management — a report of two cases with a review of the literature
BibTeX
@article{bologur2026clinical,
title = {{Clinical Characteristics and Surgical Management of Calvarial Tumors: A Single-Center Retrospective Study}},
author = {Onur Boloğur and Hakan Yılmaz and Hüseyin Berk Benek and Erdal Kıssaboylu and Engin Kayıkcı and Serkan Uçmak},
journal = {Journal of Clinical Medicine},
year = {2026},
month = oct,
doi = {10.3390/jcm15208045},
url = {https://www.mdpi.com/2077-0383/15/20/8045},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Clinical Characteristics and Surgical Management of Calvarial Tumors: A Single-Center Retrospective Study
AU - Onur Boloğur
AU - Hakan Yılmaz
AU - Hüseyin Berk Benek
AU - Erdal Kıssaboylu
AU - Engin Kayıkcı
AU - Serkan Uçmak
PY - 2026
DA - 2026/10/01
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15208045
UR - https://www.mdpi.com/2077-0383/15/20/8045
AB - Background/Objectives: Calvarial tumors form a heterogeneous group of benign and malignant lesions, and institutional series remain limited, particularly from Türkiye. This study aimed to describe the clinical, radiological, histopathological, and surgical features and histology-specific outcomes of calvarial tumors treated at a single neurosurgical center. Methods: We retrospectively reviewed 42 patients who underwent surgery for histopathologically confirmed tumors and tumor-like lesions of the cranial vault between 2019 and 2024. Clinical, imaging, histopathological, surgical, and follow-up data were analyzed. Results: The cohort comprised 24 men and 18 women (mean age 42.6 ± 15.3 years; range 7–78). A palpable mass was the most common complaint (64%), and the frontal bone was the most common site (38%). Lesions were benign in 25 patients (60%, including 6 with fibrous dysplasia) and malignant in 17 (40%); osteoma and metastasis were the leading diagnoses. Malignant tumors were larger and had a shorter symptom duration than benign lesions. Total resection was achieved in 36 patients (86%). During a mean follow-up of 32 months, recurrence occurred in 8% (95% CI 2–25%) of benign and 35% (95% CI 17–59%) of malignant tumors (p = 0.045); 8 recurrences occurred after total resection. Conclusions: In this surgical series, a short symptom duration, larger lesion size, and destructive CT features were associated with malignancy, although their diagnostic accuracy requires validation in larger cohorts. Recurrence was uncommon in those with benign lesions but occurred in about one-third of those with malignant tumors, which therefore require multidisciplinary management and close surveillance. Because recurrence also occurred after total resection, the extent of resection alone did not ensure local control.
SN - 2077-0383
ER -