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Peer-reviewedCC BYCureus

Anticoagulation Dilemma in a Patient With Pulmonary Embolism and Massive Haemoptysis.

  1. 1Adult Cardiology, Uganda Heart Institute, Kampala, UGA.

Abstract

The development of worsening haemoptysis in a patient with pulmonary embolism presents a significant treatment challenge, especially in a low-resource setting where advanced interventions such as bronchial artery embolization may not be readily available. We present the case of a 40-year-old morbidly obese woman who was transferred to our facility with recurrent lower-limb deep vein thrombosis and a new diagnosis of bilateral pulmonary embolism. Following initiation of oral anticoagulation with apixaban, she developed worsening haemoptysis that persisted despite dose adjustments. She was subsequently stabilized and discharged on a vitamin K antagonist (warfarin). This case highlights the clinical challenges encountered in managing anticoagulation in the setting of significant bleeding and underscores the importance of individualized anticoagulation therapies.

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BibTeX
@article{mugwano2026anticoagulation,
  title = {{Anticoagulation Dilemma in a Patient With Pulmonary Embolism and Massive Haemoptysis.}},
  author = {Isaac Mugwano and Faith Atim Emilly and Isaac Ssinabulya and David Salama Kaishusha and Joanita Nalyazi},
  journal = {Cureus},
  year = {2026},
  month = sep,
  doi = {10.7759/cureus.116889},
  url = {https://europepmc.org/article/MED/42928820},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Anticoagulation Dilemma in a Patient With Pulmonary Embolism and Massive Haemoptysis.
AU  - Isaac Mugwano
AU  - Faith Atim Emilly
AU  - Isaac Ssinabulya
AU  - David Salama Kaishusha
AU  - Joanita Nalyazi
PY  - 2026
DA  - 2026/09/25
JO  - Cureus
DO  - 10.7759/cureus.116889
UR  - https://europepmc.org/article/MED/42928820
AB  - The development of worsening haemoptysis in a patient with pulmonary embolism presents a significant treatment challenge, especially in a low-resource setting where advanced interventions such as bronchial artery embolization may not be readily available. We present the case of a 40-year-old morbidly obese woman who was transferred to our facility with recurrent lower-limb deep vein thrombosis and a new diagnosis of bilateral pulmonary embolism. Following initiation of oral anticoagulation with apixaban, she developed worsening haemoptysis that persisted despite dose adjustments. She was subsequently stabilized and discharged on a vitamin K antagonist (warfarin). This case highlights the clinical challenges encountered in managing anticoagulation in the setting of significant bleeding and underscores the importance of individualized anticoagulation therapies.
SN  - 2168-8184
ER  -