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Peer-reviewedCC BYClinical case reports

Clinically Suspected Tumefactive Demyelination Mimicking a Brain Tumor in a 10-Year-Old Boy: A Case Report.

7 affiliations
  1. 1Rehman Medical Institute Peshawar Pakistan.
  2. 2Peshawar Medical College Peshawar Pakistan.
  3. 3Hayatabad Medical Complex Peshawar Pakistan.
  4. 4Khyber Medical College Peshawar Pakistan.
  5. 5Kabul University of Medical Sciences (KUMS) Kabul Afghanistan.
  6. 6Camden Clark Medical Center Parkersburg West Virginia USA.
  7. 7West Virginia University Morgantown West Virginia USA.

Abstract

After cranial surgery, a 10-year-old boy developed hand weakness, numbness, and fatigue. MRI showed frontoparietal lesions; biopsy lacked documented demyelination. Symptoms and lesions reportedly improved after methylprednisolone. Tumefactive demyelination was suspected, but discordant laterality, unavailable antibody testing, and brief follow-up left the diagnosis unclassified.

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BibTeX
@article{aman2026clinically,
  title = {{Clinically Suspected Tumefactive Demyelination Mimicking a Brain Tumor in a 10-Year-Old Boy: A Case Report.}},
  author = {Fatima Aman and Ahmad Ali and Muhammad Fawad Khan and Haq Nawaz Khan and Asim Shah and Ali Sher Erkin and Suleman Khan and Yasar Sattar and Aizaz Anwar Khalid},
  journal = {Clinical case reports},
  year = {2026},
  month = nov,
  doi = {10.1002/ccr3.73887},
  url = {https://europepmc.org/article/MED/42999769},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Clinically Suspected Tumefactive Demyelination Mimicking a Brain Tumor in a 10-Year-Old Boy: A Case Report.
AU  - Fatima Aman
AU  - Ahmad Ali
AU  - Muhammad Fawad Khan
AU  - Haq Nawaz Khan
AU  - Asim Shah
AU  - Ali Sher Erkin
AU  - Suleman Khan
AU  - Yasar Sattar
AU  - Aizaz Anwar Khalid
PY  - 2026
DA  - 2026/11/06
JO  - Clinical case reports
DO  - 10.1002/ccr3.73887
UR  - https://europepmc.org/article/MED/42999769
AB  - After cranial surgery, a 10-year-old boy developed hand weakness, numbness, and fatigue. MRI showed frontoparietal lesions; biopsy lacked documented demyelination. Symptoms and lesions reportedly improved after methylprednisolone. Tumefactive demyelination was suspected, but discordant laterality, unavailable antibody testing, and brief follow-up left the diagnosis unclassified.
SN  - 2050-0904
ER  -