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Peer-reviewedCC BY-NC-ND 4.0JACC Case Reports

Left Atrial Mass as the Initial Presentation of Poorly Differentiated Nonsmall Cell Lung Carcinoma

  • Manjunath Bagur1
  • Ajmal Sahaban1
  • Vallabh Anil Manathkar1
  • Ashwin Shivamurthy Banakar1
  • Ashok Upadhyaya1
  • Vishnu Sharma2
  • Krishnaraj Upadhyaya3
  1. 1Department of Cardiology, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India
  2. 2Department of Pulmonology, A.J. Institute of Medical Sciences, Mangalore, Karnataka, India
  3. 3Department of Pathology, Yenepoya Medical College, Mangalore, Karnataka, India
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Abstract

Background: Lung carcinoma is a leading cause of cancer-related mortality globally. Although metastasis to the bone, brain, and adrenal glands is common, secondary cardiac involvement is exceptionally rare, particularly within the left atrium.

Case Presentation: A 62-year-old female patient, a known case of hypothyroidism, presented with a 6-month history of class II dyspnea on exertion and easy fatigability. She also reported a 2-month history of giddiness, chest discomfort, and weight loss. Initial 2-dimensional echocardiography revealed a large left atrial mass, suspected to be a tumor thrombus. Subsequent diagnostic evaluations, including a chest computed tomography scan and positron emission tomography, identified a primary lung carcinoma. A bronchoscopic biopsy confirmed poorly differentiated nonsmall cell lung cancer.

Conclusions: This case highlights the importance of integrating multimodal imaging to accurately diagnose atypical intracardiac masses. It also emphasizes the clinical necessity of including metastatic lung malignancy in the differential diagnosis when an intracavitary cardiac mass is discovered.

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Cite

BibTeXRIS
BibTeX
@article{bagur2026left,
  title = {{Left Atrial Mass as the Initial Presentation of Poorly Differentiated Nonsmall Cell Lung Carcinoma}},
  author = {Manjunath Bagur and Ajmal Sahaban and Vallabh Anil Manathkar and Ashwin Shivamurthy Banakar and Ashok Upadhyaya and Vishnu Sharma and Krishnaraj Upadhyaya},
  journal = {JACC Case Reports},
  year = {2026},
  month = aug,
  doi = {10.1016/j.jaccas.2026.110007},
  url = {https://doi.org/10.1016/j.jaccas.2026.110007},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Left Atrial Mass as the Initial Presentation of Poorly Differentiated Nonsmall Cell Lung Carcinoma
AU  - Manjunath Bagur
AU  - Ajmal Sahaban
AU  - Vallabh Anil Manathkar
AU  - Ashwin Shivamurthy Banakar
AU  - Ashok Upadhyaya
AU  - Vishnu Sharma
AU  - Krishnaraj Upadhyaya
PY  - 2026
DA  - 2026/08/27
JO  - JACC Case Reports
DO  - 10.1016/j.jaccas.2026.110007
UR  - https://doi.org/10.1016/j.jaccas.2026.110007
AB  - Background: Lung carcinoma is a leading cause of cancer-related mortality globally. Although metastasis to the bone, brain, and adrenal glands is common, secondary cardiac involvement is exceptionally rare, particularly within the left atrium.  Case Presentation: A 62-year-old female patient, a known case of hypothyroidism, presented with a 6-month history of class II dyspnea on exertion and easy fatigability. She also reported a 2-month history of giddiness, chest discomfort, and weight loss. Initial 2-dimensional echocardiography revealed a large left atrial mass, suspected to be a tumor thrombus. Subsequent diagnostic evaluations, including a chest computed tomography scan and positron emission tomography, identified a primary lung carcinoma. A bronchoscopic biopsy confirmed poorly differentiated nonsmall cell lung cancer.  Conclusions: This case highlights the importance of integrating multimodal imaging to accurately diagnose atypical intracardiac masses. It also emphasizes the clinical necessity of including metastatic lung malignancy in the differential diagnosis when an intracavitary cardiac mass is discovered.
SN  - 2666-0849
ER  -