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Peer-reviewedCC BY 4.0PLOS One

Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial

  • Jaya Shanker Tedla1
  • Sneha Latha Lalaji2
  • Ajaya Kumar Midde3
  • Nirmala A. Papalkar4
  • N. Bindhu Priya
  • Devika Rani Sangadala
  • Ravi Shankar Reddy
  • Debjani Mukherjee
  • Ahlam Mohammed Alamri
  • Abdullah Suwayyid Alzahrani
  • Najla Awn Alhadi
4 affiliations
  1. 1Department of Medical Rehabilitation Science, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia
  2. 2Department of Neurorehabilitation, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India
  3. 3Sr Consultant Urogynecology, Department of Urogynecology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India
  4. 4Physiotherapy Department, Armed Forces Hospital Southern Region Rehabilitation Health Services, Khamis Mushait, Saudi Arabia
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Abstract

Background: In the traditional treatment of overactive bladder (OAB) with transcutaneous posterior tibial nerve stimulation (TTNS), physical therapists currently use only transcutaneous electrical nerve stimulation (TENS). However, the literature has commonly replaced TENS with diadynamic currents for various musculoskeletal pain syndromes. Moreover, no literature describes the use of diadynamic currents in the TTNS procedure. Therefore, our study aimed to determine the efficacy of diadynamic currents (DDC) versus TENS for TTNS in OAB Treatment. Methodology: A randomized controlled trial was conducted among female patients with OAB aged 18–80 years. Subjects were randomly allocated to control and experimental groups. Participants in the control group received TTNS with TENS, and those in the experimental group underwent TTNS using DDC. Both groups received 8 TTNS sessions, two per week for 4 weeks. We measured pre- and post-intervention improvements using the International Consultation on Incontinence Questionnaire (ICIQ) for OAB and the ICIQ OAB Quality of Life (QOL). The study is registered with the Clinical Trials Registry of India under registration number CTRI/2025/12/099269. Results: The mean age of the included sample was 59.75 years. Pre- and post-intervention ICIQ-OAB and ICIQ-OAB QOL scores showed significant improvements in disease symptoms and quality of life among patients with OAB in both the control and experimental groups. Comparison of improvements between the two groups on the ICIQ questionnaires showed no significant difference (p-values of 0.87 and 0.95). Correlations between patient-related characteristics and improvements in outcome measures were also not significant. Conclusion: Eight sessions of TENS and DDC, combined with conventional physical therapy, including Kegel and breathing exercises, can reduce OAB symptoms and improve QOL in subjects with OAB syndrome. Diadynamic current can be used as an adjunct to conventional TENS in TTNS for treating OAB syndrome.

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Cite

BibTeXRIS
BibTeX
@article{tedla2026efficacy,
  title = {{Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial}},
  author = {Jaya Shanker Tedla and Sneha Latha Lalaji and Ajaya Kumar Midde and Nirmala A. Papalkar and N. Bindhu Priya and Devika Rani Sangadala and Ravi Shankar Reddy and Debjani Mukherjee and Ahlam Mohammed Alamri and Abdullah Suwayyid Alzahrani and Najla Awn Alhadi},
  journal = {PLOS One},
  year = {2026},
  month = nov,
  doi = {10.1371/journal.pone.0362118},
  url = {https://doi.org/10.1371/journal.pone.0362118},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Efficacy of diadynamic currents versus transcutaneous electrical nerve stimulation for transcutaneous tibial nerve stimulation in subjects with overactive bladder syndrome: A double-blind randomized controlled trial
AU  - Jaya Shanker Tedla
AU  - Sneha Latha Lalaji
AU  - Ajaya Kumar Midde
AU  - Nirmala A. Papalkar
AU  - N. Bindhu Priya
AU  - Devika Rani Sangadala
AU  - Ravi Shankar Reddy
AU  - Debjani Mukherjee
AU  - Ahlam Mohammed Alamri
AU  - Abdullah Suwayyid Alzahrani
AU  - Najla Awn Alhadi
PY  - 2026
DA  - 2026/11/06
JO  - PLOS One
DO  - 10.1371/journal.pone.0362118
UR  - https://doi.org/10.1371/journal.pone.0362118
AB  - Background: In the traditional treatment of overactive bladder (OAB) with transcutaneous posterior tibial nerve stimulation (TTNS), physical therapists currently use only transcutaneous electrical nerve stimulation (TENS). However, the literature has commonly replaced TENS with diadynamic currents for various musculoskeletal pain syndromes. Moreover, no literature describes the use of diadynamic currents in the TTNS procedure. Therefore, our study aimed to determine the efficacy of diadynamic currents (DDC) versus TENS for TTNS in OAB Treatment. Methodology: A randomized controlled trial was conducted among female patients with OAB aged 18–80 years. Subjects were randomly allocated to control and experimental groups. Participants in the control group received TTNS with TENS, and those in the experimental group underwent TTNS using DDC. Both groups received 8 TTNS sessions, two per week for 4 weeks. We measured pre- and post-intervention improvements using the International Consultation on Incontinence Questionnaire (ICIQ) for OAB and the ICIQ OAB Quality of Life (QOL). The study is registered with the Clinical Trials Registry of India under registration number CTRI/2025/12/099269. Results: The mean age of the included sample was 59.75 years. Pre- and post-intervention ICIQ-OAB and ICIQ-OAB QOL scores showed significant improvements in disease symptoms and quality of life among patients with OAB in both the control and experimental groups. Comparison of improvements between the two groups on the ICIQ questionnaires showed no significant difference (p-values of 0.87 and 0.95). Correlations between patient-related characteristics and improvements in outcome measures were also not significant. Conclusion: Eight sessions of TENS and DDC, combined with conventional physical therapy, including Kegel and breathing exercises, can reduce OAB symptoms and improve QOL in subjects with OAB syndrome. Diadynamic current can be used as an adjunct to conventional TENS in TTNS for treating OAB syndrome.
SN  - 1932-6203
ER  -