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Peer-reviewedCC BY-NC-ND 4.0BMC Public Health

Parental and health service-related factors influencing full pentavalent vaccine uptake among children aged 12-23 months in Nigeria: findings from the demographic and health survey

3 more authors
  1. 1Department of Community Health, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife, Osun state Nigeria
  2. 2Department of Community Health, Obafemi Awolowo University (OAU), Ile- Ife, Osun state Nigeria

Abstract

Background: Recurrent diphtheria outbreaks in Sub-Saharan African countries remain a major public health concern, which have been related with suboptimal pentavalent vaccine uptake. Nationally representative evidence on full pentavalent vaccine uptake and its determinants in Nigeria remains limited. This study aimed to assess the full pentavalent vaccine uptake and to identify associated factors among children aged 12–23 months using data from the Nigeria Demographic and Health Survey (NDHS).

Methodology: This was a population-based cross-sectional study among children aged 12–23 months selected using a multistage stratified cluster sampling design. Data were obtained from the 2024 NDHS and a total weighted sample of 1,947 children aged 12–23 months was selected for analysis. The outcome variable was full pentavalent vaccine uptake defined as receipt of 3 pentavalent vaccine doses. Using STATA 17, bivariate and multivariable analyses were conducted to identify factors associated with full pentavalent vaccine uptake. The influence of parental and health service–related factors on full pentavalent vaccine uptake was examined using adjusted odds ratios and 95% confidence intervals. Statistical significance was set at p < 0.05.

Results: The mean age of the children aged 12–23 months was 17 months (SD: 3.5), and 52.3% were male. The full pentavalent vaccine uptake was 57.6% (95% CI:54.5, 60.7). In the final adjusted regression model, children of educated mothers (AOR: 5.9; 95% CI:2.29, 14.98) and educated fathers (AOR: 2.2; 95% CI: 1.18, 4.03), children whose mothers had antenatal care visits ≥ 4 (AOR: 2.1; 95% CI: 1.55, 2.97) and had health card (AOR: 16.9; 95% CI: 11.91, 24.13) were more likely to have full pentavalent vaccine uptake.

Conclusion: The observed full pentavalent vaccine uptake (57.6%) was below the WHO African Region national target (≥ 90%). The study findings highlight gap in full pentavalent vaccine uptake and underscore the need for targeted interventions to improve full pentavalent vaccine uptake in Nigeria.

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BibTeX
@article{akeju2026parental,
  title = {{Parental and health service-related factors influencing full pentavalent vaccine uptake among children aged 12-23 months in Nigeria: findings from the demographic and health survey}},
  author = {Eyiyemi Toluwase Akeju and Dondo Jagusa Aatsav and Victoria Emike Ologun and Adewunmi Adedamola Oladosu-Adedoyin and Comfort Odedeyi and Oluyemisi Folorunso-Olabisi and Olaoti Oyeyemi Ogundare and Olubusola Caroline Olukoju and Christopher Oluwatosin Omokanye and Chinonso Mary Agrippa and Adeyemi Akeem Amuda and Kingsley Ebi Magbei and Baderinwa Opeyemi Akanji and Gift Sharon Igbaudume and Adeleye A. Adeomi},
  journal = {BMC Public Health},
  year = {2026},
  month = aug,
  doi = {10.1186/s12889-026-29027-z},
  url = {https://doi.org/10.1186/s12889-026-29027-z},
  note = {CC BY-NC-ND 4.0},
}
RIS
TY  - JOUR
TI  - Parental and health service-related factors influencing full pentavalent vaccine uptake among children aged 12-23 months in Nigeria: findings from the demographic and health survey
AU  - Eyiyemi Toluwase Akeju
AU  - Dondo Jagusa Aatsav
AU  - Victoria Emike Ologun
AU  - Adewunmi Adedamola Oladosu-Adedoyin
AU  - Comfort Odedeyi
AU  - Oluyemisi Folorunso-Olabisi
AU  - Olaoti Oyeyemi Ogundare
AU  - Olubusola Caroline Olukoju
AU  - Christopher Oluwatosin Omokanye
AU  - Chinonso Mary Agrippa
AU  - Adeyemi Akeem Amuda
AU  - Kingsley Ebi Magbei
AU  - Baderinwa Opeyemi Akanji
AU  - Gift Sharon Igbaudume
AU  - Adeleye A. Adeomi
PY  - 2026
DA  - 2026/08/13
JO  - BMC Public Health
DO  - 10.1186/s12889-026-29027-z
UR  - https://doi.org/10.1186/s12889-026-29027-z
AB  - Background: Recurrent diphtheria outbreaks in Sub-Saharan African countries remain a major public health concern, which have been related with suboptimal pentavalent vaccine uptake. Nationally representative evidence on full pentavalent vaccine uptake and its determinants in Nigeria remains limited. This study aimed to assess the full pentavalent vaccine uptake and to identify associated factors among children aged 12–23 months using data from the Nigeria Demographic and Health Survey (NDHS).  Methodology: This was a population-based cross-sectional study among children aged 12–23 months selected using a multistage stratified cluster sampling design. Data were obtained from the 2024 NDHS and a total weighted sample of 1,947 children aged 12–23 months was selected for analysis. The outcome variable was full pentavalent vaccine uptake defined as receipt of 3 pentavalent vaccine doses. Using STATA 17, bivariate and multivariable analyses were conducted to identify factors associated with full pentavalent vaccine uptake. The influence of parental and health service–related factors on full pentavalent vaccine uptake was examined using adjusted odds ratios and 95% confidence intervals. Statistical significance was set at p < 0.05.  Results: The mean age of the children aged 12–23 months was 17 months (SD: 3.5), and 52.3% were male. The full pentavalent vaccine uptake was 57.6% (95% CI:54.5, 60.7). In the final adjusted regression model, children of educated mothers (AOR: 5.9; 95% CI:2.29, 14.98) and educated fathers (AOR: 2.2; 95% CI: 1.18, 4.03), children whose mothers had antenatal care visits ≥ 4 (AOR: 2.1; 95% CI: 1.55, 2.97) and had health card (AOR: 16.9; 95% CI: 11.91, 24.13) were more likely to have full pentavalent vaccine uptake.  Conclusion: The observed full pentavalent vaccine uptake (57.6%) was below the WHO African Region national target (≥ 90%). The study findings highlight gap in full pentavalent vaccine uptake and underscore the need for targeted interventions to improve full pentavalent vaccine uptake in Nigeria.
SN  - 1471-2458
ER  -