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Peer-reviewedCC BYCurrent Problems in Cancer: Case Reports

Burned-out testicular tumor with metastatic choriocarcinoma: a case report

  • Fahredin Veselaj1
  • Suzana Manxhuka-Kerliu2
  • Rine Limani3
  • Labinota Kondirolli3
  • Flaka Pasha4
  • Kreshnike Dedushi-Hoti5
  • Kaltrina Gocaj4
5 affiliations
  1. 1Faculty of Medicine, University of Prishtina, Kosova, Department of Surgery, 10000, Kosova
  2. 2Mediterranean Task Force for Cancer Control-MTCC, Kosova
  3. 3Faculty of Medicine, University of Prishtina, Department of Pathology& Histology, Europe
  4. 4Faculty of Medicine, University of Prishtina, Department of Radiology & Oncology, Kosova
  5. 5Faculty of Medicine, University of Prishtina, Department of Radiology & Oncology, Kosova; Corresponding author.
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Abstract

Burned-out testicular tumors represent regressed primary germ cell tumors (GCTs) in which only metastatic deposits remain histologically detectable, the primary lesion having undergone spontaneous involution. Mixed germ cell tumors containing choriocarcinoma are biologically aggressive, frequently presenting with early hematogenous spread and elevated beta-human chorionic gonadotropin (β-hCG) levels. We report the case of a young man presenting with pulmonary and nodal metastases arising from a burned-out testicular mixed germ cell tumor with choriocarcinoma and embryonal carcinoma components, and we review the diagnostic, pathological, and therapeutic aspects of this entity based on the available literature. The case illustrates the diagnostic pitfall posed by a clinically inconspicuous primary tumor in a patient presenting with extensive metastatic germ cell disease, and it underscores the value of integrating tumor markers, imaging, and immunohistochemistry to reach the correct diagnosis.

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Cite

BibTeXRIS
BibTeX
@article{veselaj2026burnedout,
  title = {{Burned-out testicular tumor with metastatic choriocarcinoma: a case report}},
  author = {Fahredin Veselaj and Suzana Manxhuka-Kerliu and Rine Limani and Labinota Kondirolli and Flaka Pasha and Kreshnike Dedushi-Hoti and Kaltrina Gocaj},
  journal = {Current Problems in Cancer: Case Reports},
  year = {2026},
  month = nov,
  doi = {10.1016/j.cpccr.2026.100453},
  url = {https://doi.org/10.1016/j.cpccr.2026.100453},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Burned-out testicular tumor with metastatic choriocarcinoma: a case report
AU  - Fahredin Veselaj
AU  - Suzana Manxhuka-Kerliu
AU  - Rine Limani
AU  - Labinota Kondirolli
AU  - Flaka Pasha
AU  - Kreshnike Dedushi-Hoti
AU  - Kaltrina Gocaj
PY  - 2026
DA  - 2026/11/01
JO  - Current Problems in Cancer: Case Reports
DO  - 10.1016/j.cpccr.2026.100453
UR  - https://doi.org/10.1016/j.cpccr.2026.100453
AB  - Burned-out testicular tumors represent regressed primary germ cell tumors (GCTs) in which only metastatic deposits remain histologically detectable, the primary lesion having undergone spontaneous involution. Mixed germ cell tumors containing choriocarcinoma are biologically aggressive, frequently presenting with early hematogenous spread and elevated beta-human chorionic gonadotropin (β-hCG) levels. We report the case of a young man presenting with pulmonary and nodal metastases arising from a burned-out testicular mixed germ cell tumor with choriocarcinoma and embryonal carcinoma components, and we review the diagnostic, pathological, and therapeutic aspects of this entity based on the available literature. The case illustrates the diagnostic pitfall posed by a clinically inconspicuous primary tumor in a patient presenting with extensive metastatic germ cell disease, and it underscores the value of integrating tumor markers, imaging, and immunohistochemistry to reach the correct diagnosis.
SN  - 2666-6219
ER  -