Hepatic Metastasis of Meningioma Treated with Partial Hepatectomy: A Case Report.
- 1Department of Surgery, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan.
- 2Department of Pathology, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan.
- 3Department of Hepatology, Kagoshima Kouseiren Hospital, Kagoshima, Kagoshima, Japan.
Abstract
Introduction
Meningioma is one of the most common central nervous system tumors; however, metastatic lesions are extremely rare. Particularly, hepatic metastasis from meningioma is uncommon, and its diagnosis and optimal management remain undefined.Case presentation
A 70-year-old man with a history of left parietal meningioma resection in 2011 and gamma knife therapy for recurrence in the left lateral ventricle in June 2025. A PET-CT scan performed for cancer screening in June 2025 revealed abnormal fluorodeoxyglucose uptake in segment 8 of the liver, with a maximum standardized uptake value of 6.2. CT, and MRI revealed multiple hepatic masses. All tumor markers were within normal ranges. A percutaneous liver biopsy indicated a spindle cell tumor; however, the diagnosis remained inconclusive. For diagnostic and therapeutic purposes, partial hepatectomy of segments 6 and 8 and cholecystectomy were performed. Histopathological examination revealed proliferating spindle-shaped tumor cells arranged in fascicles. Immunohistochemical staining was positive for vimentin, epithelial membrane antigen, and somatostatin receptor 2, confirming the diagnosis of hepatic metastasis from meningioma. The postoperative course was uneventful, and the patient was discharged in good condition.Conclusions
Hepatic metastasis from meningioma is extremely rare; however, it should be considered in the differential diagnosis of hepatic tumors in patients with a history of meningioma. Surgical resection is valuable in establishing a definitive diagnosis and achieving local disease control.
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BibTeX
@article{hirase2026hepatic,
title = {{Hepatic Metastasis of Meningioma Treated with Partial Hepatectomy: A Case Report.}},
author = {Yuki Hirase and Haruhi Fukuhisa and Akihiko Sakamoto and Masahiko Sakoda and Sumika Matsukita and Takuya Hiwaki and Shigeho Maenohara},
journal = {Surgical case reports},
year = {2026},
month = oct,
doi = {10.70352/scrj.cr.26-0401},
url = {https://europepmc.org/article/MED/42894863},
note = {CC BY},
}
RIS
TY - JOUR
TI - Hepatic Metastasis of Meningioma Treated with Partial Hepatectomy: A Case Report.
AU - Yuki Hirase
AU - Haruhi Fukuhisa
AU - Akihiko Sakamoto
AU - Masahiko Sakoda
AU - Sumika Matsukita
AU - Takuya Hiwaki
AU - Shigeho Maenohara
PY - 2026
DA - 2026/10/16
JO - Surgical case reports
DO - 10.70352/scrj.cr.26-0401
UR - https://europepmc.org/article/MED/42894863
AB - Introduction Meningioma is one of the most common central nervous system tumors; however, metastatic lesions are extremely rare. Particularly, hepatic metastasis from meningioma is uncommon, and its diagnosis and optimal management remain undefined.Case presentation A 70-year-old man with a history of left parietal meningioma resection in 2011 and gamma knife therapy for recurrence in the left lateral ventricle in June 2025. A PET-CT scan performed for cancer screening in June 2025 revealed abnormal fluorodeoxyglucose uptake in segment 8 of the liver, with a maximum standardized uptake value of 6.2. CT, and MRI revealed multiple hepatic masses. All tumor markers were within normal ranges. A percutaneous liver biopsy indicated a spindle cell tumor; however, the diagnosis remained inconclusive. For diagnostic and therapeutic purposes, partial hepatectomy of segments 6 and 8 and cholecystectomy were performed. Histopathological examination revealed proliferating spindle-shaped tumor cells arranged in fascicles. Immunohistochemical staining was positive for vimentin, epithelial membrane antigen, and somatostatin receptor 2, confirming the diagnosis of hepatic metastasis from meningioma. The postoperative course was uneventful, and the patient was discharged in good condition.Conclusions Hepatic metastasis from meningioma is extremely rare; however, it should be considered in the differential diagnosis of hepatic tumors in patients with a history of meningioma. Surgical resection is valuable in establishing a definitive diagnosis and achieving local disease control.
SN - 2198-7793
ER -