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Peer-reviewedCC BYJournal for ImmunoTherapy of Cancer

321 Genome-scale CRISPR KO screen identifies PCBP2 as a tumor-intrinsic regulator of cancer cell sensitivity to human CD4+ T cell killing

  • Paul Chapman1
  • Iñaki Etxeberría2
  • Benjamin Izar3
  • Omar Abdel-Wahab4
  • Clemens Hinterleitner5
  • Michael Gormally6
  • Alexander N Shoushtari7
  • Lauren B Banks8
  • Korbinian Kropp8
  • Jeetayu Biswas8
  • Smita S Chandran8
  • Rebecca Nadler8
10 more authors
  • John Klement8
  • Jahan A Rahman8
  • Michael Mu3
  • Salima Benbarche8
  • Fei Yi8
  • Marco Ruzzo8
  • Ralph Garippa8
  • Cecilia Lezcano8
  • Michael A Postow8
  • Christopher A Klebanoff8
8 affiliations
  1. 1Rehabilitation Unit, Townsville University Hospital, Townsville, Queensland, Australia
  2. 22Memorial Sloan Kettering Cancer Center, New York, NY, USA
  3. 3Columbia University Irving Medical Center, New York, NY, USA
  4. 41Memorial Sloan Kettering Cancer Center, New York, NY, USA
  5. 53UKT, Tubingen, Germany
  6. 65Memorial Sloan Kettering Cancer Center, New York, NY, USA
  7. 7Memorial Sloan Kettering Cancer Center, New York City, NY, USA
  8. 8Memorial Sloan Kettering Cancer Center, New York, NY, USA
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Cite

BibTeXRIS
BibTeX
@article{chapman2026genomescale,
  title = {{321 Genome-scale CRISPR KO screen identifies PCBP2 as a tumor-intrinsic regulator of cancer cell sensitivity to human CD4+ T cell killing}},
  author = {Paul Chapman and Iñaki Etxeberría and Benjamin Izar and Omar Abdel-Wahab and Clemens Hinterleitner and Michael Gormally and Alexander N Shoushtari and Lauren B Banks and Korbinian Kropp and Jeetayu Biswas and Smita S Chandran and Rebecca Nadler and John Klement and Jahan A Rahman and Michael Mu and Salima Benbarche and Fei Yi and Marco Ruzzo and Ralph Garippa and Cecilia Lezcano and Michael A Postow and Christopher A Klebanoff},
  journal = {Journal for ImmunoTherapy of Cancer},
  year = {2026},
  month = nov,
  doi = {10.1136/jitc-2026-sitc2026.0321},
  url = {https://doi.org/10.1136/jitc-2026-sitc2026.0321},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - 321 Genome-scale CRISPR KO screen identifies PCBP2 as a tumor-intrinsic regulator of cancer cell sensitivity to human CD4+ T cell killing
AU  - Paul Chapman
AU  - Iñaki Etxeberría
AU  - Benjamin Izar
AU  - Omar Abdel-Wahab
AU  - Clemens Hinterleitner
AU  - Michael Gormally
AU  - Alexander N Shoushtari
AU  - Lauren B Banks
AU  - Korbinian Kropp
AU  - Jeetayu Biswas
AU  - Smita S Chandran
AU  - Rebecca Nadler
AU  - John Klement
AU  - Jahan A Rahman
AU  - Michael Mu
AU  - Salima Benbarche
AU  - Fei Yi
AU  - Marco Ruzzo
AU  - Ralph Garippa
AU  - Cecilia Lezcano
AU  - Michael A Postow
AU  - Christopher A Klebanoff
PY  - 2026
DA  - 2026/11/05
JO  - Journal for ImmunoTherapy of Cancer
DO  - 10.1136/jitc-2026-sitc2026.0321
UR  - https://doi.org/10.1136/jitc-2026-sitc2026.0321
SN  - 2051-1426
ER  -