Identification, Isolation and Genomic Characterization of an Emerging Shamonda Virus Variant Associated with Bovine Disease in Switzerland.
- 1Institute of Virology and Immunology, 3147 Mittelhaeusern, Switzerland.
- 2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
- 3Cattle Health Service Switzerland (Rindergesundheit Schweiz RGS), 3052 Zollikofen, Switzerland.
Abstract
In July 2026, an outbreak of a cattle illness characterized by high fever, diarrhea and reduced milk production, often affecting whole herds, was detected across several regions of northern Switzerland. To investigate the cause of the outbreak, a broad range of diagnostic methods was applied, including pathogen-specific RT-qPCRs, ELISA, serum neutralization test, virus isolation and metagenomic next-generation sequencing. A Shamonda virus (SHAV) was detected in samples from affected cattle, followed by successful virus isolation and complete genome sequencing of all three segments. Viral RNA was also detected in tissue samples from aborted calves, including the brain and spleen, supporting the need for further investigation of the virus in the context of reproductive disease. These findings document the first detection and molecular characterization of a SHAV in Switzerland and demonstrate its widespread circulation in cattle during the 2026 outbreak.
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BibTeX
@article{wyler2026identification,
title = {{Identification, Isolation and Genomic Characterization of an Emerging Shamonda Virus Variant Associated with Bovine Disease in Switzerland.}},
author = {Michele Wyler and Karin Darpel and Rémy Berset and Sandra Renzullo and Helen Huber and Jessica Bauer and Judith Peter-Egli and Claudia Bachofen and Jakub Kubacki},
journal = {Viruses},
year = {2026},
month = oct,
doi = {10.3390/v18101086},
url = {https://europepmc.org/article/MED/42944006},
note = {CC BY},
}
RIS
TY - JOUR
TI - Identification, Isolation and Genomic Characterization of an Emerging Shamonda Virus Variant Associated with Bovine Disease in Switzerland.
AU - Michele Wyler
AU - Karin Darpel
AU - Rémy Berset
AU - Sandra Renzullo
AU - Helen Huber
AU - Jessica Bauer
AU - Judith Peter-Egli
AU - Claudia Bachofen
AU - Jakub Kubacki
PY - 2026
DA - 2026/10/01
JO - Viruses
DO - 10.3390/v18101086
UR - https://europepmc.org/article/MED/42944006
AB - In July 2026, an outbreak of a cattle illness characterized by high fever, diarrhea and reduced milk production, often affecting whole herds, was detected across several regions of northern Switzerland. To investigate the cause of the outbreak, a broad range of diagnostic methods was applied, including pathogen-specific RT-qPCRs, ELISA, serum neutralization test, virus isolation and metagenomic next-generation sequencing. A Shamonda virus (SHAV) was detected in samples from affected cattle, followed by successful virus isolation and complete genome sequencing of all three segments. Viral RNA was also detected in tissue samples from aborted calves, including the brain and spleen, supporting the need for further investigation of the virus in the context of reproductive disease. These findings document the first detection and molecular characterization of a SHAV in Switzerland and demonstrate its widespread circulation in cattle during the 2026 outbreak.
SN - 1999-4915
ER -