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Peer-reviewedCC BY 4.0Case Reports in Orthopedics

Tumoral Calcium Pyrophosphate Deposition in the Glenohumeral Joint: A Case Report

  1. 1Department of Orthopaedic Surgery Graduate School of Biomedical and Health Sciences Hiroshima University Hiroshima Japan hiroshima-u.ac.jp
  2. 2Department of Orthopaedic Surgery Hiroshima Citizens Hospital Hiroshima Japan city-hosp.naka.hiroshima.jp

Abstract

Case: A 75‐year‐old male patient presented with long‐standing pain and swelling in the shoulder. Radiographic evaluations revealed a large, calcified mass posterior to the humeral head, without apparent bone erosion or destruction. Magnetic resonance imaging demonstrated an intra‐articular mass‐like lesion in the glenohumeral joint without apparent extension into the adjacent bone or surrounding soft tissues. Because the lesion appeared nonaggressive on imaging, a benign calcified intra‐articular lesion was initially considered. Open and arthroscopy‐assisted excision of the lesion was performed because of severe pain and restricted range of motion. Pathological examination demonstrated abundant crystalline deposits with angular and elongated morphology, consistent with calcium pyrophosphate deposition disease, leading to the diagnosis of tophaceous pseudogout. Two years after the surgery, radiography showed mild enlargement of the residual calcific deposits, although the patient remained asymptomatic.

Conclusion: Tophaceous pseudogout of the glenohumeral joint is rare and may mimic neoplastic lesions on imaging; therefore, it should be considered in the differential diagnosis of calcified masses in the shoulder.

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BibTeX
@article{watanabe2026tumoral,
  title = {{Tumoral Calcium Pyrophosphate Deposition in the Glenohumeral Joint: A Case Report}},
  author = {Chikara Watanabe and Yohei Harada and Shuhei Matsumura and Shin Yokoya and Nobuo Adachi},
  journal = {Case Reports in Orthopedics},
  year = {2026},
  month = nov,
  doi = {10.1155/cro/9540064},
  url = {https://doi.org/10.1155/cro/9540064},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Tumoral Calcium Pyrophosphate Deposition in the Glenohumeral Joint: A Case Report
AU  - Chikara Watanabe
AU  - Yohei Harada
AU  - Shuhei Matsumura
AU  - Shin Yokoya
AU  - Nobuo Adachi
PY  - 2026
DA  - 2026/11/03
JO  - Case Reports in Orthopedics
DO  - 10.1155/cro/9540064
UR  - https://doi.org/10.1155/cro/9540064
AB  - Case: A 75‐year‐old male patient presented with long‐standing pain and swelling in the shoulder. Radiographic evaluations revealed a large, calcified mass posterior to the humeral head, without apparent bone erosion or destruction. Magnetic resonance imaging demonstrated an intra‐articular mass‐like lesion in the glenohumeral joint without apparent extension into the adjacent bone or surrounding soft tissues. Because the lesion appeared nonaggressive on imaging, a benign calcified intra‐articular lesion was initially considered. Open and arthroscopy‐assisted excision of the lesion was performed because of severe pain and restricted range of motion. Pathological examination demonstrated abundant crystalline deposits with angular and elongated morphology, consistent with calcium pyrophosphate deposition disease, leading to the diagnosis of tophaceous pseudogout. Two years after the surgery, radiography showed mild enlargement of the residual calcific deposits, although the patient remained asymptomatic.  Conclusion: Tophaceous pseudogout of the glenohumeral joint is rare and may mimic neoplastic lesions on imaging; therefore, it should be considered in the differential diagnosis of calcified masses in the shoulder.
SN  - 2090-6749
SN  - 2090-6757
ER  -