Skip to content
DraconiticResearch
Search Sources API
190,839 studies31 sourcesUpdated 40 min ago
PreprintarXiv licencearXiv

Neural Structural Reasoner: A Brain-inspired Architecture for Reasoning over Structured Knowledge

Abstract

Structural reasoning, the ability to recognize and make inferences over the relational structure between objects and concepts, is a hallmark of human cognition, yet prevailing methods often collapse relational topology into flat embeddings, cannot discover hidden structure and lack interpretability. We introduce Neural Structural Reasoner (NSR), a brain-inspired network that preserves relational structure directly in the connectivity and dynamics of coupled neuronal populations. NSR draws inspiration from three biological mechanisms: multi-layered architecture for encoding hierarchical knowledge, stable representations of entity and concepts, and path integration for input-driven state inference. At query time, NSR parallelizes computation over candidate relational structures and leverages confidence-weighted scores to perform link prediction. Across standard knowledge-graph benchmarks, NSR achieves competitive accuracy without leading on every dataset, and has lower reported training times than several neural baselines. Because reasoning is implemented through sequences of human-readable neuron activations, NSR affords native interpretability by tracking intermediate inference steps. The model further extracts latent relational hierarchies and compositional rules, demonstrating the brain-inspired architecture as an effective, efficient, and highly interpretable substrate for structural reasoning.

Related

  1. Stable large-scale network architecture and structured individual variability in the awake mouse brain
    Y. Zou, R. Tu, C. Zhang +10
    bioRxivPreprintAll rights reservedFull textNeurosciencebioRxiv
  2. MedEvo: Medical Reasoning Evolution through Knowledge Navigation
    Xiaoliang Wang, Zhuo Chen, Chuanyang Zheng +11
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  3. CircuitATLAS: Agentic reasoning over a systems neuroscience knowledge graph for target discovery in circuitopathies
    Gabriel Ocana-Santero, Marko Tvrdic
    arXivPreprintCC BY-NC-ND 4.0Full textBioinformatics & computational biologyNeurosciencearXiv
  4. From structured knowledge to flexible behaviour: the importance of local prefrontal computations
    Mohamady El-Gaby, Kris Jensen, Svenja Kuechenhoff +7
    PsyArXivPreprintCC BY 4.0Full textNeuroscienceOSF
  5. Knowledge-Enriched Structured EHR Features for 30-Day Hospital Readmission Prediction on MIMIC-IV
    Mohamad Najafi, Hongyun Fu, Mathias Brochhausen +2
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
BibTeX
@misc{jia2026neural,
  title = {{Neural Structural Reasoner: A Brain-inspired Architecture for Reasoning over Structured Knowledge}},
  author = {Zixing Jia and Yuhang Pan and Ni Ji},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.36620},
  eprint = {2609.36620},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.36620},
}
RIS
TY  - UNPB
TI  - Neural Structural Reasoner: A Brain-inspired Architecture for Reasoning over Structured Knowledge
AU  - Zixing Jia
AU  - Yuhang Pan
AU  - Ni Ji
PY  - 2026
DA  - 2026/09/29
PB  - arXiv
DO  - 10.48550/arxiv.2609.36620
UR  - https://arxiv.org/abs/2609.36620
AB  - Structural reasoning, the ability to recognize and make inferences over the relational structure between objects and concepts, is a hallmark of human cognition, yet prevailing methods often collapse relational topology into flat embeddings, cannot discover hidden structure and lack interpretability. We introduce Neural Structural Reasoner (NSR), a brain-inspired network that preserves relational structure directly in the connectivity and dynamics of coupled neuronal populations. NSR draws inspiration from three biological mechanisms: multi-layered architecture for encoding hierarchical knowledge, stable representations of entity and concepts, and path integration for input-driven state inference. At query time, NSR parallelizes computation over candidate relational structures and leverages confidence-weighted scores to perform link prediction. Across standard knowledge-graph benchmarks, NSR achieves competitive accuracy without leading on every dataset, and has lower reported training times than several neural baselines. Because reasoning is implemented through sequences of human-readable neuron activations, NSR affords native interpretability by tracking intermediate inference steps. The model further extracts latent relational hierarchies and compositional rules, demonstrating the brain-inspired architecture as an effective, efficient, and highly interpretable substrate for structural reasoning.
ER  -