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Peer-reviewedCC BY 4.0Journal of General Internal Medicine

Implementation of a Hospital-Based Screening and Treatment Program for Unhealthy Alcohol Use

8 affiliations
  1. 1Department of Internal Medicine, Dell Medical School at The University of Texas at Austin, Austin, TX USA
  2. 2Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA USA
  3. 3Department of Medicine, University of California, Los Angeles, Los Angeles, CA USA
  4. 4CommUnity Care Health Centers, Austin, TX USA
  5. 5Central Health, Travis County Health District, Austin, TX USA
  6. 6Department of Population Health, Dell Medical School at The University of Texas at Austin, Austin, TX USA
  7. 7The University of Texas at Austin, Steve Hicks School of Social Work, Austin, TX USA
  8. 8Department of Medicine, Duke University, Durham, NC USA

Abstract

Background: Screening and treatment for unhealthy alcohol use (UAU) and alcohol use disorder (AUD) are recommended but underutilized, particularly in hospital settings.

Objective: To determine whether a comprehensive screening and treatment protocol for UAU in hospitalized patients can help reduce alcohol use.

Design: Quality improvement study at single-center safety-net hospital.

Participants: 27,914 patients were admitted from 9/2022 to 9/2024, and 18,146 (65.0%) were screened with AUDIT-PC, with 1085 (6.0%) screening positive (≥ 5). Substance use navigators (SUNs) identified 257 additional patients with UAU through referral methods.

Intervention: SUNs approached eligible patients and conducted full AUDIT and brief behavioral counseling. Patients with AUDIT ≥ 12 were offered medications for AUD (MAUD) during hospitalization and at discharge.

Main Measures: Intervention delivery, 30-day return hospital encounters (readmission or emergency department), and change in AUDIT score among high-risk patients.

Key Results: Of the 1342 intervention-eligible patients, 81% were men, and the mean age was 51 years. 54% were Caucasian, 30% Hispanic/Latinx, and 9% Black. 17% were unhoused, and 18% were uninsured. Of these 1342, 800 (59.6%) patients engaged in the intervention. The mean AUDIT score was 15 (median 14, IQR 8–21). For the 489 (61.1%) patients with AUDIT ≥ 12, 231 (47.2%) were started on medication before discharge. For the 126 patients with repeat AUDIT (25.8%), the mean reduction was 14.2 points (95% CI: −15.4, −12.2). For those with AUDIT ≥ 12, 128 (26.2%) patients had a return hospital encounter within 30 days of discharge. Patients without return encounters had significantly larger reductions in AUDIT score than those who had return encounters (mean reduction −16.2 vs −9.1 points (difference −7.1, 95% CI: −3.1, −11.0)).

Conclusions: UAU screening and risk-stratified treatment (including pharmacotherapy) can be delivered in diverse hospitalized patients, and were accompanied by short-term changes in alcohol risk score among patients reached for follow-up.

Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s11606-026-10473-9.

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BibTeX
@article{ramesh2026implementation,
  title = {{Implementation of a Hospital-Based Screening and Treatment Program for Unhealthy Alcohol Use}},
  author = {Jananie Ramesh and Christopher Moriates and John Embers and Alanna Boulton and Nicole Kluz and Rachel Holliman and Frances Ibarra and Ohenewaa Dede-Bamfo and Patrick Chang and Mary Velasquez and Michael Pignone},
  journal = {Journal of General Internal Medicine},
  year = {2026},
  month = may,
  doi = {10.1007/s11606-026-10473-9},
  url = {https://doi.org/10.1007/s11606-026-10473-9},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Implementation of a Hospital-Based Screening and Treatment Program for Unhealthy Alcohol Use
AU  - Jananie Ramesh
AU  - Christopher Moriates
AU  - John Embers
AU  - Alanna Boulton
AU  - Nicole Kluz
AU  - Rachel Holliman
AU  - Frances Ibarra
AU  - Ohenewaa Dede-Bamfo
AU  - Patrick Chang
AU  - Mary Velasquez
AU  - Michael Pignone
PY  - 2026
DA  - 2026/05/14
JO  - Journal of General Internal Medicine
DO  - 10.1007/s11606-026-10473-9
UR  - https://doi.org/10.1007/s11606-026-10473-9
AB  - Background: Screening and treatment for unhealthy alcohol use (UAU) and alcohol use disorder (AUD) are recommended but underutilized, particularly in hospital settings.  Objective: To determine whether a comprehensive screening and treatment protocol for UAU in hospitalized patients can help reduce alcohol use.  Design: Quality improvement study at single-center safety-net hospital.  Participants: 27,914 patients were admitted from 9/2022 to 9/2024, and 18,146 (65.0%) were screened with AUDIT-PC, with 1085 (6.0%) screening positive (≥ 5). Substance use navigators (SUNs) identified 257 additional patients with UAU through referral methods.  Intervention: SUNs approached eligible patients and conducted full AUDIT and brief behavioral counseling. Patients with AUDIT ≥ 12 were offered medications for AUD (MAUD) during hospitalization and at discharge.  Main Measures: Intervention delivery, 30-day return hospital encounters (readmission or emergency department), and change in AUDIT score among high-risk patients.  Key Results: Of the 1342 intervention-eligible patients, 81% were men, and the mean age was 51 years. 54% were Caucasian, 30% Hispanic/Latinx, and 9% Black. 17% were unhoused, and 18% were uninsured. Of these 1342, 800 (59.6%) patients engaged in the intervention. The mean AUDIT score was 15 (median 14, IQR 8–21). For the 489 (61.1%) patients with AUDIT ≥ 12, 231 (47.2%) were started on medication before discharge. For the 126 patients with repeat AUDIT (25.8%), the mean reduction was 14.2 points (95% CI: −15.4, −12.2). For those with AUDIT ≥ 12, 128 (26.2%) patients had a return hospital encounter within 30 days of discharge. Patients without return encounters had significantly larger reductions in AUDIT score than those who had return encounters (mean reduction −16.2 vs −9.1 points (difference −7.1, 95% CI: −3.1, −11.0)).  Conclusions: UAU screening and risk-stratified treatment (including pharmacotherapy) can be delivered in diverse hospitalized patients, and were accompanied by short-term changes in alcohol risk score among patients reached for follow-up.  Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s11606-026-10473-9.
SN  - 0884-8734
SN  - 1525-1497
ER  -