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Peer-reviewedCC BY 4.0International Journal of Antimicrobial Agents

Outcomes for persons with triple-class resistant HIV and a history of virologic failure

  • Suzanne M Ingle
  • Fabrice Bonnet
  • Linda Wittkop
  • Alexandra Calmy
  • Ramon Teira
  • Peter F Rebeiro
  • Heidi M Crane
  • Christoph Stephan
  • Marc van der Valk
  • Christoph Boesecke
  • Giota Touloumi
  • M. John Gill
7 more authors
  • Katharina Grabmeier-Pfistershammer
  • Federico Garcia
  • Francesca Ceccherini-Silberstein
  • Greer Burkholder
  • Adam Trickey
  • Jonathan a C Sterne
  • Mojgan Hessamfar
Open at sourcePDFDOICite

Abstract

stop TRIO without switching (8.8%); and death on TRIO (7.2%). Conclusions: Although the most common outcome after TRIO was switch to another three or more drug regimen, almost one third of virologically suppressed PWH under TRIO (with a history of multidrug resistance) switched to a drug-reducing regimen, the majority of whom maintained suppression.

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Cite

BibTeXRIS
BibTeX
@article{ingle2026outcomes,
  title = {{Outcomes for persons with triple-class resistant HIV and a history of virologic failure}},
  author = {Suzanne M Ingle and Fabrice Bonnet and Linda Wittkop and Alexandra Calmy and Ramon Teira and Peter F Rebeiro and Heidi M Crane and Christoph Stephan and Marc van der Valk and Christoph Boesecke and Giota Touloumi and M. John Gill and Katharina Grabmeier-Pfistershammer and Federico Garcia and Francesca Ceccherini-Silberstein and Greer Burkholder and Adam Trickey and Jonathan a C Sterne and Mojgan Hessamfar},
  journal = {International Journal of Antimicrobial Agents},
  year = {2026},
  month = sep,
  doi = {10.1016/j.ijantimicag.2026.107925},
  url = {https://hal.science/hal-05737404v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Outcomes for persons with triple-class resistant HIV and a history of virologic failure
AU  - Suzanne M Ingle
AU  - Fabrice Bonnet
AU  - Linda Wittkop
AU  - Alexandra Calmy
AU  - Ramon Teira
AU  - Peter F Rebeiro
AU  - Heidi M Crane
AU  - Christoph Stephan
AU  - Marc van der Valk
AU  - Christoph Boesecke
AU  - Giota Touloumi
AU  - M. John Gill
AU  - Katharina Grabmeier-Pfistershammer
AU  - Federico Garcia
AU  - Francesca Ceccherini-Silberstein
AU  - Greer Burkholder
AU  - Adam Trickey
AU  - Jonathan a C Sterne
AU  - Mojgan Hessamfar
PY  - 2026
DA  - 2026/09/03
JO  - International Journal of Antimicrobial Agents
DO  - 10.1016/j.ijantimicag.2026.107925
UR  - https://hal.science/hal-05737404v1
AB  - stop TRIO without switching (8.8%); and death on TRIO (7.2%). Conclusions: Although the most common outcome after TRIO was switch to another three or more drug regimen, almost one third of virologically suppressed PWH under TRIO (with a history of multidrug resistance) switched to a drug-reducing regimen, the majority of whom maintained suppression.
SN  - 0924-8579
SN  - 1872-7913
ER  -