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Peer-reviewedCC BY-NC-SAJournal of Indira Gandhi Institute of Medical Sciences

Etiological spectrum of acute febrile illness in adult males in Eastern India: A cross-sectional observational study

Abstract

Background: This cross-sectional observational study, conducted at a tertiary care center in Eastern India from January 2021 to June 2022, investigated the etiological spectrum of acute febrile illness (AFI) in adult males (>14 years). Methods: We analyzed data of 3218 serological tests for dengue, malaria, enteric fever, scrub typhus, and leptospirosis from consecutive samples. Results: The overall positivity rate was 9.04%, with enteric fever (17.54% Typhidot, 13.80% Widal), scrub typhus (17.73%), dengue (7.35%), leptospirosis (3.20%), and malaria (0.24%) identified. Bacterial infections predominated. Rural and urban distributions varied, with leptospirosis showing higher urban prevalence (83.33%) and scrub typhus more common in rural areas (59.57%), with positivity peaks in September-December 2021. Conclusion: This study reveals the diverse etiologies of AFI in adult males in Eastern India, with bacterial etiologies such as enteric fever and scrub typhus predominating from September to December 2021, emphasizing the need for integrated diagnostics approaches, to guide clinical management and strengthened sanitation and vector control in this endemic setting.

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BibTeX
@article{priyanka2026etiological,
  title = {{Etiological spectrum of acute febrile illness in adult males in Eastern India: A cross-sectional observational study}},
  author = {R K Priyanka and Nidhi Prasad and Manoj Kumar Chaudhary and Dipali Prasad and Amit Kumar and Rakesh Kumar and Shishir Kumar and Anusha Prasad},
  journal = {Journal of Indira Gandhi Institute of Medical Sciences},
  year = {2026},
  month = jul,
  doi = {10.4103/jigims.jigims_79_25},
  url = {https://doi.org/10.4103/jigims.jigims_79_25},
  note = {CC BY-NC-SA},
}
RIS
TY  - JOUR
TI  - Etiological spectrum of acute febrile illness in adult males in Eastern India: A cross-sectional observational study
AU  - R K Priyanka
AU  - Nidhi Prasad
AU  - Manoj Kumar Chaudhary
AU  - Dipali Prasad
AU  - Amit Kumar
AU  - Rakesh Kumar
AU  - Shishir Kumar
AU  - Anusha Prasad
PY  - 2026
DA  - 2026/07/01
JO  - Journal of Indira Gandhi Institute of Medical Sciences
DO  - 10.4103/jigims.jigims_79_25
UR  - https://doi.org/10.4103/jigims.jigims_79_25
AB  - Background: This cross-sectional observational study, conducted at a tertiary care center in Eastern India from January 2021 to June 2022, investigated the etiological spectrum of acute febrile illness (AFI) in adult males (>14 years). Methods: We analyzed data of 3218 serological tests for dengue, malaria, enteric fever, scrub typhus, and leptospirosis from consecutive samples. Results: The overall positivity rate was 9.04%, with enteric fever (17.54% Typhidot, 13.80% Widal), scrub typhus (17.73%), dengue (7.35%), leptospirosis (3.20%), and malaria (0.24%) identified. Bacterial infections predominated. Rural and urban distributions varied, with leptospirosis showing higher urban prevalence (83.33%) and scrub typhus more common in rural areas (59.57%), with positivity peaks in September-December 2021. Conclusion: This study reveals the diverse etiologies of AFI in adult males in Eastern India, with bacterial etiologies such as enteric fever and scrub typhus predominating from September to December 2021, emphasizing the need for integrated diagnostics approaches, to guide clinical management and strengthened sanitation and vector control in this endemic setting.
SN  - 2394-9031
SN  - 2582-094X
ER  -