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Peer-reviewedCC BY-NC-NDInternal Medicine

The Use of Vessel Wall Imaging for Making an Early Diagnosis of Giant Cell Arteritis in a Case with Cerebral Infarction

Abstract

We report a rare case of giant cell arteritis (GCA) initially presenting as ischemic stroke in the perforating branch territory. An 81-year-old woman presented with dysarthria and was diagnosed with a right midbrain and pontine infarction. Six months later, the patient developed recurrent dysarthria and left hemiparesis. Magnetic resonance imaging (MRI) revealed a new right lenticulostriate infarct, and magnetic resonance angiography showed rapidly progressive intracranial stenosis. Vessel wall MRI demonstrated concentric enhancement in the intracranial and extracranial arteries. A temporal artery biopsy confirmed the presence of GCA. This case highlights the diagnostic value of vessel wall imaging for detecting intracranial involvement in GCA.

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BibTeX
@article{yamamoto2026vessel,
  title = {{The Use of Vessel Wall Imaging for Making an Early Diagnosis of Giant Cell Arteritis in a Case with Cerebral Infarction}},
  author = {Masaomi Yamamoto and Tomohisa Dembo and Tetsuo Yamaga and Shuji Momose and Satoru Oji and Kenichi Kaida},
  journal = {Internal Medicine},
  year = {2026},
  month = jul,
  doi = {10.2169/internalmedicine.6532-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/14/65_6532-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - The Use of Vessel Wall Imaging for Making an Early Diagnosis of Giant Cell Arteritis in a Case with Cerebral Infarction
AU  - Masaomi Yamamoto
AU  - Tomohisa Dembo
AU  - Tetsuo Yamaga
AU  - Shuji Momose
AU  - Satoru Oji
AU  - Kenichi Kaida
PY  - 2026
DA  - 2026/07/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6532-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/14/65_6532-25/_article
AB  - We report a rare case of giant cell arteritis (GCA) initially presenting as ischemic stroke in the perforating branch territory. An 81-year-old woman presented with dysarthria and was diagnosed with a right midbrain and pontine infarction. Six months later, the patient developed recurrent dysarthria and left hemiparesis. Magnetic resonance imaging (MRI) revealed a new right lenticulostriate infarct, and magnetic resonance angiography showed rapidly progressive intracranial stenosis. Vessel wall MRI demonstrated concentric enhancement in the intracranial and extracranial arteries. A temporal artery biopsy confirmed the presence of GCA. This case highlights the diagnostic value of vessel wall imaging for detecting intracranial involvement in GCA.
SN  - 1349-7235
SN  - 0918-2918
ER  -