Periodontal indices in patients with chronic obstructive pulmonary disease and their correlation with disease severity: A cross-sectional study.
4 affiliations
- 1Dental Implants Research Center Department of Periodontics, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
- 2Dental Students' Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
- 3Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
- 4Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract
Background
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition primarily influenced by oral microbiota, which is the source of the microbiome. This study evaluated selected periodontal indices in COPD patients and their relationship with COPD severity among patients referred to Khorshid Hospital and Day Clinic in Isfahan in 2023.Methods
This cross-sectional study involved 221 subjects diagnosed with COPD based on spirometry testing. According to spirometry values, the subjects were classified into mild, moderate, severe, and very severe COPD categories. Periodontal indices including pocket depth (PD), bleeding on probing (BOP), plaque index (PI) and clinical attachment loss (CAL), were assessed. In addition, relevant demographic and medical information, along with smoking status and severity of periodontal disease, were evaluated. The data were analyzed using one-way ANOVA, chi-square test, t-test, and rank regression with SPSS software.Results
All evaluated patients had periodontitis. Overall, higher COPD grades were associated with increased periodontal disease indices (PD, BOP, PI, and CAL) (p<0.001). Greater periodontitis severity correlated with increased COPD severity, with moderate and severe periodontitis raising the risk of severe and very severe COPD by 8.1 and nearly 62 times, respectively. In severe and very severe COPD cases, periodontal disease severity showed the highest level of association with COPD severity compared to age and pack-years of smoking.Conclusion
COPD severity significantly correlated with PD, BOP, PI, and CAL. However, further clinical studies are needed to establish a definitive association between these conditions due to the shared pathophysiology of COPD and periodontal disease.
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BibTeX
@article{naghsh2026periodontal,
title = {{Periodontal indices in patients with chronic obstructive pulmonary disease and their correlation with disease severity: A cross-sectional study.}},
author = {Narges Naghsh and Seyed Mehdi Shahshahan and Faeze Karimi and Mohammad Javad Tarrahi and Ramin Sami},
journal = {Caspian journal of internal medicine},
year = {2026},
month = sep,
doi = {10.22088/cjim.17.3.562},
url = {https://europepmc.org/article/MED/42923669},
note = {CC BY-NC},
}
RIS
TY - JOUR
TI - Periodontal indices in patients with chronic obstructive pulmonary disease and their correlation with disease severity: A cross-sectional study.
AU - Narges Naghsh
AU - Seyed Mehdi Shahshahan
AU - Faeze Karimi
AU - Mohammad Javad Tarrahi
AU - Ramin Sami
PY - 2026
DA - 2026/09/01
JO - Caspian journal of internal medicine
DO - 10.22088/cjim.17.3.562
UR - https://europepmc.org/article/MED/42923669
AB - Background Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition primarily influenced by oral microbiota, which is the source of the microbiome. This study evaluated selected periodontal indices in COPD patients and their relationship with COPD severity among patients referred to Khorshid Hospital and Day Clinic in Isfahan in 2023.Methods This cross-sectional study involved 221 subjects diagnosed with COPD based on spirometry testing. According to spirometry values, the subjects were classified into mild, moderate, severe, and very severe COPD categories. Periodontal indices including pocket depth (PD), bleeding on probing (BOP), plaque index (PI) and clinical attachment loss (CAL), were assessed. In addition, relevant demographic and medical information, along with smoking status and severity of periodontal disease, were evaluated. The data were analyzed using one-way ANOVA, chi-square test, t-test, and rank regression with SPSS software.Results All evaluated patients had periodontitis. Overall, higher COPD grades were associated with increased periodontal disease indices (PD, BOP, PI, and CAL) (p<0.001). Greater periodontitis severity correlated with increased COPD severity, with moderate and severe periodontitis raising the risk of severe and very severe COPD by 8.1 and nearly 62 times, respectively. In severe and very severe COPD cases, periodontal disease severity showed the highest level of association with COPD severity compared to age and pack-years of smoking.Conclusion COPD severity significantly correlated with PD, BOP, PI, and CAL. However, further clinical studies are needed to establish a definitive association between these conditions due to the shared pathophysiology of COPD and periodontal disease.
SN - 2008-6164
SN - 2008-6172
ER -