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Peer-reviewedCC BYClinical Case Reports

Anti‐U1‐RNP‐Positive Inflammatory Myopathy Presenting With Dysphagia: A Case Report

  • Anjlee1
  • Sana Rasheed2
  • Moosa Ashfaq2
  • Simran Bai3
  • Ali Jan Yaqubi4
  • Ahmed Asad Raza2
4 affiliations
  1. 1Department of Medicine and Surgery Ghulam Muhammad Mahar Medical College Sukkur Pakistan
  2. 2Department of Medicine and Surgery Jinnah Sindh Medical University Karachi Pakistan
  3. 3Department of General Medicine Jinnah Postgraduate Medical Center Karachi Pakistan
  4. 4Department of Medicine Kabul University of Medical Sciences Abu Ali Sina Kabul Afghanistan
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Abstract

High‐titer anti‐U1‐RNP antibodies may present with myopathy without fulfilling MCTD criteria. We report a 38‐year‐old woman with proximal weakness, elevated muscle enzymes, anti‐U1‐RNP positivity, and inflammatory myopathy on EMG/MRI, but lacking classic overlap features. Early recognition enabled immunosuppressive treatment and prevention of aspiration‐related complications.

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Cite

BibTeXRIS
BibTeX
@article{anjlee2026antiu1rnppositive,
  title = {{Anti‐U1‐RNP‐Positive Inflammatory Myopathy Presenting With Dysphagia: A Case Report}},
  author = {Anjlee and Sana Rasheed and Moosa Ashfaq and Simran Bai and Ali Jan Yaqubi and Ahmed Asad Raza},
  journal = {Clinical Case Reports},
  year = {2026},
  month = oct,
  doi = {10.1002/ccr3.73676},
  url = {https://doi.org/10.1002/ccr3.73676},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Anti‐U1‐RNP‐Positive Inflammatory Myopathy Presenting With Dysphagia: A Case Report
AU  - Anjlee
AU  - Sana Rasheed
AU  - Moosa Ashfaq
AU  - Simran Bai
AU  - Ali Jan Yaqubi
AU  - Ahmed Asad Raza
PY  - 2026
DA  - 2026/10/23
JO  - Clinical Case Reports
DO  - 10.1002/ccr3.73676
UR  - https://doi.org/10.1002/ccr3.73676
AB  - High‐titer anti‐U1‐RNP antibodies may present with myopathy without fulfilling MCTD criteria. We report a 38‐year‐old woman with proximal weakness, elevated muscle enzymes, anti‐U1‐RNP positivity, and inflammatory myopathy on EMG/MRI, but lacking classic overlap features. Early recognition enabled immunosuppressive treatment and prevention of aspiration‐related complications.
SN  - 2050-0904
ER  -