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Peer-reviewedLicence not statedDrug discovery today

Methadone: Historical success, modern challenges and lessons for opioid drug discovery

  • Ennian Li1
  • Preet Shah1
  • Yan Zhang1,2,3,4
4 affiliations
  1. 1Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, 800 East Leigh Street, Richmond, VA 23298, USA
  2. 2Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, 410 North 12th Street, Richmond, VA 23298, USA
  3. 3Center for Drug Discovery, Virginia Commonwealth University, 800 East Leigh Street, Richmond, VA 23298, USA
  4. 4Institute for Drug and Alcohol Studies, Virginia Commonwealth University, 203 East Cary Street, Richmond, VA 23298, USA
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Cite

BibTeXRIS
BibTeX
@article{li2026methadone,
  title = {{Methadone: Historical success, modern challenges and lessons for opioid drug discovery}},
  author = {Ennian Li and Preet Shah and Yan Zhang},
  journal = {Drug discovery today},
  year = {2026},
  month = oct,
  doi = {10.1016/j.drudis.2026.104840},
  url = {https://doi.org/10.1016/j.drudis.2026.104840},
}
RIS
TY  - JOUR
TI  - Methadone: Historical success, modern challenges and lessons for opioid drug discovery
AU  - Ennian Li
AU  - Preet Shah
AU  - Yan Zhang
PY  - 2026
DA  - 2026/10/23
JO  - Drug discovery today
DO  - 10.1016/j.drudis.2026.104840
UR  - https://doi.org/10.1016/j.drudis.2026.104840
SN  - 1359-6446
SN  - 1878-5832
ER  -