Impact of an early extended rehabilitation programme combining individually tailored nutrition and physical activity on patient outcomes after invasive mechanical ventilation and vasopressor therapy in the ICU: design and conduct of a multicentre, randomised, controlled, open-label, assessor-blinded trial (NUTRIREA-4)

@article{reignier2026impact,
  title = {{Impact of an early extended rehabilitation programme combining individually tailored nutrition and physical activity on patient outcomes after invasive mechanical ventilation and vasopressor therapy in the ICU: design and conduct of a multicentre, randomised, controlled, open-label, assessor-blinded trial (NUTRIREA-4)}},
  author = {Jean Reignier and Soraya Benguerfi and Emeline Corbin and Diane Maugars and Ronan Thibault and Adam Jirka and Thomas Cattagni and Antoine Nordez and Laurent Argaud and Julio Badie and Maxime Bertrand and Alexandra Beurton and Matthieu Boiffier and Nicolae-Vlad Botoc and Claire Bourel and Anne-Astrid Bourion and Akli Chermak and Michael Darmon and Matthieu Debarre and Agathe Delbove and Maxime Desgrouas and Jérôme Devaquet and Louis-Marie Galerneau and Quentin Georges and Vivien Guillotin and Laurent Guérin and Christophe Henry and Jean-Etienne Herbrecht and Samir Jaber and Béatrice La Combe and Laurent Lainé and Fabien Lambiotte and Mickael Landais and Julien Maizel and Stéphanie Malaquin and Thomas Maldiney and Virginie Maxime and Emmanuelle Mercier and Hamid Merdji and Jean-Paul Mira and Elise Morawiec and Damien Muller and Olivier Nigeon and Thibaut Noel and Marc Pierrot and Gael Piton and Gaetan Plantefeve and Jean-Pierre Quenot and Jean Philippe Rigaud and Marion Rougon and Clément Saccheri and Ghada Sboui and Daniel Silva and Bertrand Souweine and Jean Marc Tadie and Fabienne Tamion and Guillaume Thiery and Thierry Vanderlinden and Isabelle Vinatier and Robin Souron},
  journal = {BMJ Open},
  year = {2026},
  month = oct,
  doi = {10.1136/bmjopen-2026-127985},
  url = {https://hal.science/hal-05828544v1},
  note = {CC BY 4.0},
}

TY  - JOUR
TI  - Impact of an early extended rehabilitation programme combining individually tailored nutrition and physical activity on patient outcomes after invasive mechanical ventilation and vasopressor therapy in the ICU: design and conduct of a multicentre, randomised, controlled, open-label, assessor-blinded trial (NUTRIREA-4)
AU  - Jean Reignier
AU  - Soraya Benguerfi
AU  - Emeline Corbin
AU  - Diane Maugars
AU  - Ronan Thibault
AU  - Adam Jirka
AU  - Thomas Cattagni
AU  - Antoine Nordez
AU  - Laurent Argaud
AU  - Julio Badie
AU  - Maxime Bertrand
AU  - Alexandra Beurton
AU  - Matthieu Boiffier
AU  - Nicolae-Vlad Botoc
AU  - Claire Bourel
AU  - Anne-Astrid Bourion
AU  - Akli Chermak
AU  - Michael Darmon
AU  - Matthieu Debarre
AU  - Agathe Delbove
AU  - Maxime Desgrouas
AU  - Jérôme Devaquet
AU  - Louis-Marie Galerneau
AU  - Quentin Georges
AU  - Vivien Guillotin
AU  - Laurent Guérin
AU  - Christophe Henry
AU  - Jean-Etienne Herbrecht
AU  - Samir Jaber
AU  - Béatrice La Combe
AU  - Laurent Lainé
AU  - Fabien Lambiotte
AU  - Mickael Landais
AU  - Julien Maizel
AU  - Stéphanie Malaquin
AU  - Thomas Maldiney
AU  - Virginie Maxime
AU  - Emmanuelle Mercier
AU  - Hamid Merdji
AU  - Jean-Paul Mira
AU  - Elise Morawiec
AU  - Damien Muller
AU  - Olivier Nigeon
AU  - Thibaut Noel
AU  - Marc Pierrot
AU  - Gael Piton
AU  - Gaetan Plantefeve
AU  - Jean-Pierre Quenot
AU  - Jean Philippe Rigaud
AU  - Marion Rougon
AU  - Clément Saccheri
AU  - Ghada Sboui
AU  - Daniel Silva
AU  - Bertrand Souweine
AU  - Jean Marc Tadie
AU  - Fabienne Tamion
AU  - Guillaume Thiery
AU  - Thierry Vanderlinden
AU  - Isabelle Vinatier
AU  - Robin Souron
PY  - 2026
DA  - 2026/10/20
JO  - BMJ Open
DO  - 10.1136/bmjopen-2026-127985
UR  - https://hal.science/hal-05828544v1
SN  - 2044-6055
ER  -