Synthesis, Structure and Antibacterial Activity of a Neutral Tin(II) Iodide Complex with 1,2-bis[(4-Methoxyphenyl)imino]acenaphthene
- 1Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, 31 Leninsky prosp., 119991 Moscow, Russia
- 2D. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya Square, 125047 Moscow, Russia
- 3Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, 49 Tropinina Street, 603137 Nizhny Novgorod, Russia
Abstract
The reaction of tin(II) iodide with 1,2-bis[(4-methoxyphenyl)imino]acenaphthene (4-MeO-BIAN) in anhydrous tetrahydrofuran afforded the neutral complex [(4-MeO-BIAN)SnI(μ-I)]2 (1). A single-phase sample of 1 was isolated and characterized by powder X-ray diffraction and IR spectroscopy. The crystal structure of 1 was determined by single-crystal X-ray diffraction: a centrosymmetric dimeric structure with an Sn2I2 core formed by two μ2-bridging iodide ligands; each Sn(II) center is additionally coordinated by a bidentate 4-MeO-BIAN ligand and one terminal iodide ligand. The antibacterial activity of 1 was evaluated in vitro against clinically significant Gram-positive (Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis) and Gram-negative (Escherichia coli) bacteria. Complex 1 exhibited moderate antibacterial activity against all tested strains, with MIC values of 40–312.5 µg/mL and MBC values of 62.5–312.5 µg/mL. The lowest MIC values, close to those of meropenem (MIC = 32 µg/mL), were obtained against Staphylococcus aureus (MIC = 40 µg/mL).
Related
- Versatile and efficient synthesis of bis(phosphate) alkyl esters and first evidence for their antibacterial activity against Gram-positive bacteria
- Structure-activity relationship of Cu(II) and Pd(II) thiosemicarbazone complexes with anticancer and antibacterial properties
- Eco-friendly synthesis and multifunctional characterization of ZrO₂/Cu₄O₃/MnO₂/CuMnO₂ nanocomposite with enhanced thermal stability and antibacterial activity.
- Hydrothermal Synthesis of Water-Dispersible Fluorescent Carbon Dots from Renewable Plant Precursors: Antibacterial Activity and Comparative Characterization
- Synthesis of colloidal silver-polyphenols nanocomplexes - physicochemical properties, DFT calculation, modeling of adsorption and antibacterial activity
BibTeX
@article{tychinina2026synthesis,
title = {{Synthesis, Structure and Antibacterial Activity of a Neutral Tin(II) Iodide Complex with 1,2-bis[(4-Methoxyphenyl)imino]acenaphthene}},
author = {Anna A. Tychinina and Ivan V. Smolyaninov and Natalia V. Gogoleva and Anton N. Lukoyanov and Dmitriy S. Yambulatov and Mikhail A. Kiskin},
journal = {Molecules},
year = {2026},
month = oct,
doi = {10.3390/molecules31203676},
url = {https://www.mdpi.com/1420-3049/31/20/3676},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Synthesis, Structure and Antibacterial Activity of a Neutral Tin(II) Iodide Complex with 1,2-bis[(4-Methoxyphenyl)imino]acenaphthene
AU - Anna A. Tychinina
AU - Ivan V. Smolyaninov
AU - Natalia V. Gogoleva
AU - Anton N. Lukoyanov
AU - Dmitriy S. Yambulatov
AU - Mikhail A. Kiskin
PY - 2026
DA - 2026/10/01
JO - Molecules
DO - 10.3390/molecules31203676
UR - https://www.mdpi.com/1420-3049/31/20/3676
AB - The reaction of tin(II) iodide with 1,2-bis[(4-methoxyphenyl)imino]acenaphthene (4-MeO-BIAN) in anhydrous tetrahydrofuran afforded the neutral complex [(4-MeO-BIAN)SnI(μ-I)]2 (1). A single-phase sample of 1 was isolated and characterized by powder X-ray diffraction and IR spectroscopy. The crystal structure of 1 was determined by single-crystal X-ray diffraction: a centrosymmetric dimeric structure with an Sn2I2 core formed by two μ2-bridging iodide ligands; each Sn(II) center is additionally coordinated by a bidentate 4-MeO-BIAN ligand and one terminal iodide ligand. The antibacterial activity of 1 was evaluated in vitro against clinically significant Gram-positive (Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis) and Gram-negative (Escherichia coli) bacteria. Complex 1 exhibited moderate antibacterial activity against all tested strains, with MIC values of 40–312.5 µg/mL and MBC values of 62.5–312.5 µg/mL. The lowest MIC values, close to those of meropenem (MIC = 32 µg/mL), were obtained against Staphylococcus aureus (MIC = 40 µg/mL).
SN - 1420-3049
ER -