Tracheal Schwannoma Diagnosed by Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy (EBUS-IFB).
- 1Department of Respiratory Medicine NHO Nagoya Medical Center Nagoya Japan.
Abstract
Definitively diagnosing submucosal airway lesions is often challenging because conventional endobronchial forceps biopsies cannot access the deeper tissues. Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) has improved diagnostic yield for mediastinal lymph nodes; however, its application to submucosal airway lesions has not been reported. A 72-year-old man was referred to our institution because of a tracheal tumour incidentally discovered via computed tomography. Bronchoscopy revealed a broad-based, smooth-surfaced, elevated lesion involving the deep subepithelial to intramural layers. EBUS-transbronchial needle aspiration (TBNA) followed by EBUS-IFB via the puncture tract was performed. Although TBNA was inconclusive, the EBUS-IFB specimen preserved the tissue architecture with palisading spindle cells positive for S-100 and SOX10, confirming tracheal schwannoma. No complications occurred. This case suggests that EBUS-IFB may be a feasible diagnostic option for selected predominantly submucosal airway lesions when conventional sampling is inconclusive.
Related
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- Cytology smears from endobronchial ultrasound-guided transbronchial needle aspiration as a source of nucleic acids with adequate yield for next-generation sequencing
- Assessing diagnostic concordance between rapid on-site evaluation and final histopathology in mediastinal lesions using conventional and endobronchial ultrasound-guided TBNA
- Is endobronchial ultrasound-guided bronchoscopy (EBUS) transbronchial needle aspiration (TBNA) enough for the diagnosis of mediastinal lymphadenopathy? A cohort analysis
- Contrast-Enhanced Ultrasound Combined With Biopsy for the Preoperative Diagnosis of a Rare Pelvic Schwannoma: A Case Report.
BibTeX
@article{baba2026tracheal,
title = {{Tracheal Schwannoma Diagnosed by Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy (EBUS-IFB).}},
author = {Tomoya Baba and Masahide Oki and Toshihiro Ohama and Yo Imaeda and Kayo Nomura and Atsushi Torii},
journal = {Respirology case reports},
year = {2026},
month = oct,
doi = {10.1002/rcr2.70790},
url = {https://europepmc.org/article/MED/42903714},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Tracheal Schwannoma Diagnosed by Endobronchial Ultrasound-Guided Intranodal Forceps Biopsy (EBUS-IFB).
AU - Tomoya Baba
AU - Masahide Oki
AU - Toshihiro Ohama
AU - Yo Imaeda
AU - Kayo Nomura
AU - Atsushi Torii
PY - 2026
DA - 2026/10/20
JO - Respirology case reports
DO - 10.1002/rcr2.70790
UR - https://europepmc.org/article/MED/42903714
AB - Definitively diagnosing submucosal airway lesions is often challenging because conventional endobronchial forceps biopsies cannot access the deeper tissues. Endobronchial ultrasound-guided intranodal forceps biopsy (EBUS-IFB) has improved diagnostic yield for mediastinal lymph nodes; however, its application to submucosal airway lesions has not been reported. A 72-year-old man was referred to our institution because of a tracheal tumour incidentally discovered via computed tomography. Bronchoscopy revealed a broad-based, smooth-surfaced, elevated lesion involving the deep subepithelial to intramural layers. EBUS-transbronchial needle aspiration (TBNA) followed by EBUS-IFB via the puncture tract was performed. Although TBNA was inconclusive, the EBUS-IFB specimen preserved the tissue architecture with palisading spindle cells positive for S-100 and SOX10, confirming tracheal schwannoma. No complications occurred. This case suggests that EBUS-IFB may be a feasible diagnostic option for selected predominantly submucosal airway lesions when conventional sampling is inconclusive.
SN - 2051-3380
ER -