Skip to content
DraconiticResearch
Search Sources API
201,818 studies31 sourcesUpdated 59 min ago
Peer-reviewedLicence not statedNature

A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics

  • Rodion Gordzevich1,2,3
  • Min Xu1,2,3,4
  • W Wang1,2,3
  • M. A. Cook1,2,3
  • Dirk Hackenberger1,2,3
  • Julia Patricia Deisinger1,2,3
  • M. M. Tu1,2,3
  • Lindsey A. Carfrae1,2,3
  • M. George1,2,3
  • K. Rachwalski1,2,3
  • Kalinka K. Koteva1,2,3
  • David Sychantha1,2,5,3
3 more authors
  • A. Wei1,2,3
  • Gerard D. Wright6,7,8
  • Eric D. Brown9,10,11
11 affiliations
  1. 1Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada
  2. 2David Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada
  3. 3Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada
  4. 4State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Science, Tianjin, China
  5. 5Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada
  6. 6Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. [email protected]
  7. 7David Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada. [email protected]
  8. 8Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada. [email protected]
  9. 9Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada. [email protected]
  10. 10David Braley Centre for Antibiotic Discovery, McMaster University, Hamilton, Ontario, Canada. [email protected]
  11. 11Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada. [email protected]
Open at sourcePDFDOICite

Related

  1. Developmental and molecular features shaping broad and synergistic actions of human autoantibodies targeting interferon-α
    Kevin Groen, Jacques A. Moritz, Sheena Vasquez +23
    bioRxivPreprintCC BYFull textImmunologybioRxivPMC
  2. Synergistic nanotheranostic platform for fluorescence/magnetic resonance bimodal imaging-guided near infrared photoimmuno-chemodynamic thermal targeting therapy.
    Kohei Matsuoka, Mizuki Yamada, Ryu Okada +12
    Journal of nanobiotechnologyPeer-reviewedCC BY-NC-NDFull textSystems & synthetic biologyGeneral medicineEurope PMCDOAJ
  3. Subthalamic Nucleus dynamically encodes reward value and cognitive flexibility
    J. Cornish, G. Zhou, M. Reading +2
    bioRxivPreprintAll rights reservedFull textNeurosciencebioRxiv
  4. A Galbonolide-producing Streptomyces reconfigures the plant root microbiota by activating salicylate-dependent defence metabolism
    Clément Nicolle, Mohamed Zouaoui, Rémi Pendaries +5
    HALPreprintLicence not statedFull textPlant biologyHAL
  5. Title: The Cyanobacterial dnaX Intein Encodes an Out-of-Frame Homing Endonuclease and is Sporadically Distributed in the Phylum
    D. Phillips, S. DeSimone, J. P. Gogarten
    bioRxivPreprintAll rights reservedFull textMicrobiologybioRxiv

Cite

BibTeXRIS
BibTeX
@article{gordzevich2026streptomyces,
  title = {{A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics}},
  author = {Rodion Gordzevich and Min Xu and W Wang and M. A. Cook and Dirk Hackenberger and Julia Patricia Deisinger and M. M. Tu and Lindsey A. Carfrae and M. George and K. Rachwalski and Kalinka K. Koteva and David Sychantha and A. Wei and Gerard D. Wright and Eric D. Brown},
  journal = {Nature},
  year = {2026},
  month = jun,
  doi = {10.1038/s41586-026-10647-9},
  url = {https://doi.org/10.1101/2025.10.09.681295},
}
RIS
TY  - JOUR
TI  - A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics
AU  - Rodion Gordzevich
AU  - Min Xu
AU  - W Wang
AU  - M. A. Cook
AU  - Dirk Hackenberger
AU  - Julia Patricia Deisinger
AU  - M. M. Tu
AU  - Lindsey A. Carfrae
AU  - M. George
AU  - K. Rachwalski
AU  - Kalinka K. Koteva
AU  - David Sychantha
AU  - A. Wei
AU  - Gerard D. Wright
AU  - Eric D. Brown
PY  - 2026
DA  - 2026/06/24
JO  - Nature
DO  - 10.1038/s41586-026-10647-9
UR  - https://doi.org/10.1101/2025.10.09.681295
SN  - 0028-0836
SN  - 1476-4687
ER  -