Nanostructure of PEGDA-PEG hydrogel membranes and how it controls their permeability
Abstract
The spacial heterogeneity of hydrogels composed of PEGDA and added polymer chains is expected to play a crucial role on their transport properties which can be exploited in filtration or tissue engineering. However little is known about the arrangement of the polymer chains in the matrix and the length scales of these heterogeneities. Here we combine solid-state NMR and Small Angle Neutron Scattering to unravel the structure and dynamics of PEGDA hydrogels containing added PEG chains of various concentrations. Our results show that the samples present heterogeneities in both the PEGDA and PEG concentrations and suggest that the PEG chains entangle with the PEGDA network. When plotting the sample permeability, K, as a function the specific surface of the PEGDA heterogeneities we obtain a master curve, showing that the heterogeneity of the PEGDA matrix controls the permeability of the sample. Moreover the scaling K ∝ V/S suggests a structure composed of facetted PEGDA/PEG heterogeneities separated by a network of aqueous thin and flattened films in which the water can permeate.
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BibTeX
@misc{chateauneufrandon2026nanostructure,
title = {{Nanostructure of PEGDA-PEG hydrogel membranes and how it controls their permeability}},
author = {Sixtine de Chateauneuf-Randon and Malak Alaa Eddine and Bruno Bresson and Thomas Salez and Sylvain Prévost and S. Belbekhouche and Théo Merland and Cédric Lorthioir and Clémence Le Coeur and C. Monteux},
howpublished = {HAL},
year = {2026},
month = oct,
eprint = {2605.11719},
archivePrefix = {arXiv},
url = {https://hal.science/hal-05616163v2},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - UNPB
TI - Nanostructure of PEGDA-PEG hydrogel membranes and how it controls their permeability
AU - Sixtine de Chateauneuf-Randon
AU - Malak Alaa Eddine
AU - Bruno Bresson
AU - Thomas Salez
AU - Sylvain Prévost
AU - S. Belbekhouche
AU - Théo Merland
AU - Cédric Lorthioir
AU - Clémence Le Coeur
AU - C. Monteux
PY - 2026
DA - 2026/10/15
PB - HAL
UR - https://hal.science/hal-05616163v2
AB - The spacial heterogeneity of hydrogels composed of PEGDA and added polymer chains is expected to play a crucial role on their transport properties which can be exploited in filtration or tissue engineering. However little is known about the arrangement of the polymer chains in the matrix and the length scales of these heterogeneities. Here we combine solid-state NMR and Small Angle Neutron Scattering to unravel the structure and dynamics of PEGDA hydrogels containing added PEG chains of various concentrations. Our results show that the samples present heterogeneities in both the PEGDA and PEG concentrations and suggest that the PEG chains entangle with the PEGDA network. When plotting the sample permeability, K, as a function the specific surface of the PEGDA heterogeneities we obtain a master curve, showing that the heterogeneity of the PEGDA matrix controls the permeability of the sample. Moreover the scaling K ∝ V/S suggests a structure composed of facetted PEGDA/PEG heterogeneities separated by a network of aqueous thin and flattened films in which the water can permeate.
ER -