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Peer-reviewedCC BY 4.0Nano Research

Gadolinium-based hybrid polyionic complexes as versatile precursors for Prussian blue-like nanoparticles with enhanced MRI relaxivity

Abstract

Gd-based hybrid polyionic complexes are employed as versatile precursors to generate Prussian blue–like nanoparticles using two complementary strategies: (i) direct formation through the addition of K4[Fe(CN)6], and (ii) post-modification of preformed Prussian blue nanoparticles. The resulting colloids are characterized in terms of size, morphology, and colloidal stability. Their magnetic resonance relaxivity is then systematically evaluated to assess their performance as magnetic resonance imaging (MRI) contrast agents. These Gd-containing Prussian blue–like nanoparticles exhibit enhanced relaxivity compared to conventional molecular Gd complexes, highlighting their strong potential as efficient and safer MRI contrast agents.

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BibTeX
@article{peng2026gadoliniumbased,
  title = {{Gadolinium-based hybrid polyionic complexes as versatile precursors for Prussian blue-like nanoparticles with enhanced MRI relaxivity}},
  author = {Liming Peng and Florence Benoît-Marquié and Jean-Daniel Marty},
  journal = {Nano Research},
  year = {2026},
  month = aug,
  doi = {10.26599/nr.2026.94909018},
  url = {https://hal.science/hal-05731969v1},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Gadolinium-based hybrid polyionic complexes as versatile precursors for Prussian blue-like nanoparticles with enhanced MRI relaxivity
AU  - Liming Peng
AU  - Florence Benoît-Marquié
AU  - Jean-Daniel Marty
PY  - 2026
DA  - 2026/08/28
JO  - Nano Research
DO  - 10.26599/nr.2026.94909018
UR  - https://hal.science/hal-05731969v1
AB  - Gd-based hybrid polyionic complexes are employed as versatile precursors to generate Prussian blue–like nanoparticles using two complementary strategies: (i) direct formation through the addition of K4[Fe(CN)6], and (ii) post-modification of preformed Prussian blue nanoparticles. The resulting colloids are characterized in terms of size, morphology, and colloidal stability. Their magnetic resonance relaxivity is then systematically evaluated to assess their performance as magnetic resonance imaging (MRI) contrast agents. These Gd-containing Prussian blue–like nanoparticles exhibit enhanced relaxivity compared to conventional molecular Gd complexes, highlighting their strong potential as efficient and safer MRI contrast agents.
SN  - 1998-0124
SN  - 1998-0000
ER  -