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Peer-reviewedCC BYAsian biomedicine : research, reviews and news

The efficacy of ginger for treating chemotherapy-induced nausea and vomiting in patients with cancer: a systematic review and meta-analysis

  • Min Li1
  • Qianjun Li1
  • Xuecheng Zeng2
  • Misbah Ullah Khan3
  • Wei Cai1
  1. 1Department of Pharmacy , Yibin Second Hospital of Traditional Chinese Medicine , ,
  2. 2Department of Outpatient , Yibin Second Hospital of Traditional Chinese Medicine , ,
  3. 3Center for Nanosciences , University of Okara , ,
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Abstract

Background

Ginger has been shown to effectively decrease the risk of nausea and vomiting in different medical conditions. In this meta-analysis, we investigated the effect of ginger on the risk of nausea and vomiting after chemotherapy.Methods

We searched the Cochrane Library, Scopus, PubMed, and Web of Science from inception to April 17, 2025, to identify randomized controlled trials assessing the effect of ginger on the incidence of nausea and vomiting after chemotherapy.Results

Finally, we included 13 randomized controlled trials with 639 participants in the ginger group and 626 participants in the comparator group assessing the efficacy of ginger for chemotherapy-induced nausea and vomiting. Overall, the risk of bias was generally low, with only 2 studies showing high risks of bias. We found that ginger could not significantly lower the risk of acute nausea (RR 0.83, 95% CI (0.60, 1.15), I ² = 38.35%) and acute vomiting (RR 0.73, 95% CI [0.51, 1.06], I ² = 0.00%) after chemotherapy. Similarly, ginger did not significantly decrease the risk of delayed nausea (RR 0.92, 95% CI [0.66, 1.28], I ² = 23.71%) and delayed vomiting (RR 1.17, 95% CI [0.75, 1.83], I ² = 17.43%) among those receiving emetogenic chemotherapy. In subgroup analysis, age was the only factor associated with the preventive effect of ginger on chemotherapy-induced nausea and vomiting, and ginger was more effective among those younger than 50 years.Conclusion

This meta-analysis indicated that ginger could not significantly alter the risk of nausea and vomiting after chemotherapy.

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Cite

BibTeXRIS
BibTeX
@article{li2026efficacy,
  title = {{The efficacy of ginger for treating chemotherapy-induced nausea and vomiting in patients with cancer: a systematic review and meta-analysis}},
  author = {Min Li and Qianjun Li and Xuecheng Zeng and Misbah Ullah Khan and Wei Cai},
  journal = {Asian biomedicine : research, reviews and news},
  year = {2026},
  month = aug,
  doi = {10.2478/abm-2026-0030},
  url = {https://europepmc.org/article/PMC/PMC13718367},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - The efficacy of ginger for treating chemotherapy-induced nausea and vomiting in patients with cancer: a systematic review and meta-analysis
AU  - Min Li
AU  - Qianjun Li
AU  - Xuecheng Zeng
AU  - Misbah Ullah Khan
AU  - Wei Cai
PY  - 2026
DA  - 2026/08/31
JO  - Asian biomedicine : research, reviews and news
DO  - 10.2478/abm-2026-0030
UR  - https://europepmc.org/article/PMC/PMC13718367
AB  - Background  Ginger has been shown to effectively decrease the risk of nausea and vomiting in different medical conditions. In this meta-analysis, we investigated the effect of ginger on the risk of nausea and vomiting after chemotherapy.Methods  We searched the Cochrane Library, Scopus, PubMed, and Web of Science from inception to April 17, 2025, to identify randomized controlled trials assessing the effect of ginger on the incidence of nausea and vomiting after chemotherapy.Results  Finally, we included 13 randomized controlled trials with 639 participants in the ginger group and 626 participants in the comparator group assessing the efficacy of ginger for chemotherapy-induced nausea and vomiting. Overall, the risk of bias was generally low, with only 2 studies showing high risks of bias. We found that ginger could not significantly lower the risk of acute nausea (RR 0.83, 95% CI (0.60, 1.15), I ² = 38.35%) and acute vomiting (RR 0.73, 95% CI [0.51, 1.06], I ² = 0.00%) after chemotherapy. Similarly, ginger did not significantly decrease the risk of delayed nausea (RR 0.92, 95% CI [0.66, 1.28], I ² = 23.71%) and delayed vomiting (RR 1.17, 95% CI [0.75, 1.83], I ² = 17.43%) among those receiving emetogenic chemotherapy. In subgroup analysis, age was the only factor associated with the preventive effect of ginger on chemotherapy-induced nausea and vomiting, and ginger was more effective among those younger than 50 years.Conclusion  This meta-analysis indicated that ginger could not significantly alter the risk of nausea and vomiting after chemotherapy.
SN  - 1905-7415
SN  - 1875-855X
ER  -