Treat-and-repair Strategy for Atrial Septal Defect with Eisenmenger Syndrome due to Pulmonary Arterial…

Abstract

A 53-year-old man with Eisenmenger syndrome (ES), caused by a large secundum atrial septal defect (ASD) and severe pulmonary arterial hypertension (PAH), showed a marked hemodynamic improvement following an escalation of PAH-specific therapy. Surgical ASD closure using a fenestrated patch was successfully performed after a significant reduction in both the patient's pulmonary pressure and vascular resistance. This case highlights the potential utility of the "treat-and-repair" strategy in patients with ES and severe PAH, who exhibit a favorable response to medical therapy, resulting in both a symptomatic and hemodynamic improvement.

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Cite

BibTeX RIS

BibTeX

@article{kadota2026treatandrepair,
  title = {{Treat-and-repair Strategy for Atrial Septal Defect with Eisenmenger Syndrome due to Pulmonary Arterial Hypertension}},
  author = {Muneyuki Kadota and Shusuke Yagi and Satoshi Akagi and Shingo Kasahara and Issei Yagi and Shingo Hashimoto and Yoshihito Saijo and Yutaka Kawabata and Tomonori Takahashi and Tomomi Matsuura and Takayuki Ise and Koji Yamaguchi and Hirotsugu Yamada and Takeshi Soeki and Masataka Sata},
  journal = {Internal Medicine},
  year = {2026},
  month = sep,
  doi = {10.2169/internalmedicine.5948-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/17/65_5948-25/_article},
  note = {CC BY-NC-ND},
}

RIS

TY  - JOUR
TI  - Treat-and-repair Strategy for Atrial Septal Defect with Eisenmenger Syndrome due to Pulmonary Arterial Hypertension
AU  - Muneyuki Kadota
AU  - Shusuke Yagi
AU  - Satoshi Akagi
AU  - Shingo Kasahara
AU  - Issei Yagi
AU  - Shingo Hashimoto
AU  - Yoshihito Saijo
AU  - Yutaka Kawabata
AU  - Tomonori Takahashi
AU  - Tomomi Matsuura
AU  - Takayuki Ise
AU  - Koji Yamaguchi
AU  - Hirotsugu Yamada
AU  - Takeshi Soeki
AU  - Masataka Sata
PY  - 2026
DA  - 2026/09/01
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.5948-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/17/65_5948-25/_article
AB  - A 53-year-old man with Eisenmenger syndrome (ES), caused by a large secundum atrial septal defect (ASD) and severe pulmonary arterial hypertension (PAH), showed a marked hemodynamic improvement following an escalation of PAH-specific therapy. Surgical ASD closure using a fenestrated patch was successfully performed after a significant reduction in both the patient's pulmonary pressure and vascular resistance. This case highlights the potential utility of the "treat-and-repair" strategy in patients with ES and severe PAH, who exhibit a favorable response to medical therapy, resulting in both a symptomatic and hemodynamic improvement.
SN  - 1349-7235
SN  - 0918-2918
ER  -