Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance
Abstract
The incessant developments in the pharmaceutical and biomedical fields, particularly, customised solutions for specific diseases with targeted therapeutic treatments, require the design of multicomponent materials with multifunctional capabilities. Biodegradable polymers offer a variety of tailored physicochemical properties minimising health adverse side effects at a low price and weight, which are ideal to design matrices for hybrid materials. PLAs emerge as an ideal candidate to develop novel materials as are endowed withcombined ambivalent performance parameters. The state-of-the-art of use of PLA-based materials aimed at pharmaceutical and biomedical applications is reviewed, with an emphasis on the correlation between the synthesis and the processing conditions that define the nanostructure generated, with the final performance studies typically conducted with either therapeutic agents by in vitro and/or in vivo experiments or biomedical devices.
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BibTeX
@article{moyalopez2026polylactide,
title = {{Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance}},
author = {Carmen Moya-Lopez and Joaquín González-Fuentes and Iván Bravo and David Chapron and Patrice Bourson and Carlos Alonso-Moreno and Daniel Hermida-Merino},
journal = {Pharmaceutics},
year = {2026},
month = sep,
doi = {10.3390/pharmaceutics14081673},
url = {https://hal.univ-lorraine.fr/hal-03781182v1},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Polylactide Perspectives in Biomedicine: From Novel Synthesis to the Application Performance
AU - Carmen Moya-Lopez
AU - Joaquín González-Fuentes
AU - Iván Bravo
AU - David Chapron
AU - Patrice Bourson
AU - Carlos Alonso-Moreno
AU - Daniel Hermida-Merino
PY - 2026
DA - 2026/09/09
JO - Pharmaceutics
DO - 10.3390/pharmaceutics14081673
UR - https://hal.univ-lorraine.fr/hal-03781182v1
AB - The incessant developments in the pharmaceutical and biomedical fields, particularly, customised solutions for specific diseases with targeted therapeutic treatments, require the design of multicomponent materials with multifunctional capabilities. Biodegradable polymers offer a variety of tailored physicochemical properties minimising health adverse side effects at a low price and weight, which are ideal to design matrices for hybrid materials. PLAs emerge as an ideal candidate to develop novel materials as are endowed withcombined ambivalent performance parameters. The state-of-the-art of use of PLA-based materials aimed at pharmaceutical and biomedical applications is reviewed, with an emphasis on the correlation between the synthesis and the processing conditions that define the nanostructure generated, with the final performance studies typically conducted with either therapeutic agents by in vitro and/or in vivo experiments or biomedical devices.
SN - 1999-4923
ER -