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Peer-reviewedCC BY 4.0JACC: Case Reports

Catheter-Based Ventricular Assist Device–Induced Severe Hyperthermia

  • Sarah Noorani, MD1
  • Tyson Burnham, MD1
  • Eric Zuniga, MD, MBA1
  • Antonio H. Frangieh, MD, MPH2
  • Andy Y. Lee, MD3
  1. 1Department of Medicine, University of California-Irvine Medical Center, Orange, California, USA
  2. 2Department of Medicine, University of California-Irvine Medical Center, Orange, California, USA; Mary & Steve Wen Cardiovascular Division, University of California-Irvine Health, Irvine, California, USA
  3. 3Mary & Steve Wen Cardiovascular Division, University of California-Irvine Health, Irvine, California, USA; Jeffrey M. Carlton Heart & Vascular Institute, Hoag Memorial Hospital Presbyterian, Newport Beach, California, USA
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Abstract

Background: Hemolysis is a potential complication of catheter-based ventricular assist devices (CVADs), but severe hyperthermia is a rare occurrence that significantly affects further management and outcomes. Case Summary: A young man with toxic methamphetamine-associated cardiomyopathy presented with cardiogenic shock, prompting placement of a CVAD. He soon developed severe hyperthermia unresponsive to cooling measures. The hyperthermia ultimately subsided with removal of the device. Discussion: Hemolysis and renal failure are known complications of CVAD placement. The hyperthermia in this patient was likely related to erythrocytosis, highly viscous blood, and resulting hemolysis. The patient returned to normothermia only after removal of the device, supporting the idea that the CVAD was a cause of hyperthermic episode. Take-Home Messages: The use of CVADs in cardiogenic shock offers favorable outcomes but has potential complications. This unique case of severe hyperthermia resulting from massive hemolysis that required prompt removal of the device supports a rare, high-morbidity potential complication.

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Cite

BibTeXRIS
BibTeX
@article{sarahnoorani2026catheterbased,
  title = {{Catheter-Based Ventricular Assist Device–Induced Severe Hyperthermia}},
  author = {Sarah Noorani, MD and Tyson Burnham, MD and Eric Zuniga, MD, MBA and Antonio H. Frangieh, MD, MPH and Andy Y. Lee, MD},
  journal = {JACC: Case Reports},
  year = {2026},
  month = sep,
  doi = {10.1016/j.jaccas.2026.110201},
  url = {https://doi.org/10.1016/j.jaccas.2026.110201},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Catheter-Based Ventricular Assist Device–Induced Severe Hyperthermia
AU  - Sarah Noorani, MD
AU  - Tyson Burnham, MD
AU  - Eric Zuniga, MD, MBA
AU  - Antonio H. Frangieh, MD, MPH
AU  - Andy Y. Lee, MD
PY  - 2026
DA  - 2026/09/02
JO  - JACC: Case Reports
DO  - 10.1016/j.jaccas.2026.110201
UR  - https://doi.org/10.1016/j.jaccas.2026.110201
AB  - Background: Hemolysis is a potential complication of catheter-based ventricular assist devices (CVADs), but severe hyperthermia is a rare occurrence that significantly affects further management and outcomes. Case Summary: A young man with toxic methamphetamine-associated cardiomyopathy presented with cardiogenic shock, prompting placement of a CVAD. He soon developed severe hyperthermia unresponsive to cooling measures. The hyperthermia ultimately subsided with removal of the device. Discussion: Hemolysis and renal failure are known complications of CVAD placement. The hyperthermia in this patient was likely related to erythrocytosis, highly viscous blood, and resulting hemolysis. The patient returned to normothermia only after removal of the device, supporting the idea that the CVAD was a cause of hyperthermic episode. Take-Home Messages: The use of CVADs in cardiogenic shock offers favorable outcomes but has potential complications. This unique case of severe hyperthermia resulting from massive hemolysis that required prompt removal of the device supports a rare, high-morbidity potential complication.
SN  - 2666-0849
ER  -