Dietary and Nutritional Considerations for Metabolic Dysfunction-Associated Steatotic Liver Disease in Psoriasis and Hidradenitis Suppurativa: A Narrative Review
10 affiliations
- 1National Skin Centre, 1 Mandalay Road, Singapore 308205, Singapore
- 2Specialist Care Group, Diabetes and Endocrinology Centre, Mount Elizabeth Medical Centre, Singapore 228510, Singapore
- 3Department of Gastroenterology & Hepatology, Changi General Hospital, Singapore 529889, Singapore
- 4Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore
- 5Department of Medicine and Therapeutics, Medical Data Analytics Centre (MDAC), 9/F Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, Hong Kong SAR, China
- 6Institute of Digestive Disease, Hong Kong SAR, China
- 7Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China
- 8Skin Research Institute of Singapore, Singapore 308205, Singapore
- 9Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore
- 10Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore
Abstract
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognised in patients with chronic inflammatory skin disease, particularly psoriasis, for which epidemiological evidence of increased MASLD prevalence is relatively strong; corresponding data in hidradenitis suppurativa (HS) remain more limited. This narrative review examines the epidemiological and biological links between psoriasis, HS and MASLD, and evaluates dietary and nutritional strategies relevant to their multidisciplinary management. Particular emphasis is placed on distinguishing direct evidence in patients with concomitant inflammatory skin disease and MASLD from evidence derived from dermatology cohorts without liver-specific outcomes and from general MASLD populations. Mediterranean-style dietary patterns, energy restriction and weight loss, improved diet quality, and reduced intake of ultra-processed foods and added sugars are supported principally by MASLD and cardiometabolic data, with more limited direct evidence in psoriasis or HS. The review also discusses nutritional considerations during incretin-based therapy, including reduced food intake, preservation of lean mass, micronutrient adequacy and gastrointestinal adverse effects, while highlighting areas in which recommendations remain extrapolated or expert-derived. For dermatologists, the practical emphasis is on recognition of metabolic risk, general dietary counselling and appropriate multidisciplinary referral. Overall, nutritional management is an important component of MASLD care, but dedicated intervention studies in patients with concomitant psoriasis or HS remain a major evidence gap.
Related
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- Male-predominant, perianal-prone hidradenitis suppurativa in China: A cohort study of 614 patients.
- Real-world patient journey and unmet needs of people with hidradenitis suppurativa: Social media research in China.
BibTeX
@article{tay2026dietary,
title = {{Dietary and Nutritional Considerations for Metabolic Dysfunction-Associated Steatotic Liver Disease in Psoriasis and Hidradenitis Suppurativa: A Narrative Review}},
author = {Woo Chiao Tay and Choon Fong Liew and Yu Jun Wong and Grace Lai-Hung Wong and Hazel H. Oon},
journal = {Nutrients},
year = {2026},
month = oct,
doi = {10.3390/nu18193253},
url = {https://europepmc.org/article/PMC/PMC13666952},
note = {CC BY},
}
RIS
TY - JOUR
TI - Dietary and Nutritional Considerations for Metabolic Dysfunction-Associated Steatotic Liver Disease in Psoriasis and Hidradenitis Suppurativa: A Narrative Review
AU - Woo Chiao Tay
AU - Choon Fong Liew
AU - Yu Jun Wong
AU - Grace Lai-Hung Wong
AU - Hazel H. Oon
PY - 2026
DA - 2026/10/01
JO - Nutrients
DO - 10.3390/nu18193253
UR - https://europepmc.org/article/PMC/PMC13666952
AB - Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognised in patients with chronic inflammatory skin disease, particularly psoriasis, for which epidemiological evidence of increased MASLD prevalence is relatively strong; corresponding data in hidradenitis suppurativa (HS) remain more limited. This narrative review examines the epidemiological and biological links between psoriasis, HS and MASLD, and evaluates dietary and nutritional strategies relevant to their multidisciplinary management. Particular emphasis is placed on distinguishing direct evidence in patients with concomitant inflammatory skin disease and MASLD from evidence derived from dermatology cohorts without liver-specific outcomes and from general MASLD populations. Mediterranean-style dietary patterns, energy restriction and weight loss, improved diet quality, and reduced intake of ultra-processed foods and added sugars are supported principally by MASLD and cardiometabolic data, with more limited direct evidence in psoriasis or HS. The review also discusses nutritional considerations during incretin-based therapy, including reduced food intake, preservation of lean mass, micronutrient adequacy and gastrointestinal adverse effects, while highlighting areas in which recommendations remain extrapolated or expert-derived. For dermatologists, the practical emphasis is on recognition of metabolic risk, general dietary counselling and appropriate multidisciplinary referral. Overall, nutritional management is an important component of MASLD care, but dedicated intervention studies in patients with concomitant psoriasis or HS remain a major evidence gap.
SN - 2072-6643
ER -