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Peer-reviewedCC BYJournal of applied physiology (Bethesda, Md. : 1985)

Exploring the Placental Lipidome in Physically Active vs. Inactive Pregnancies

  • Meaghan L. MacDonald1
  • Anahita Yadegari1
  • Justine T. Chittaro1
  • Arthur Dantas1
  • Karl Wasslen2
  • Christian A. Rosales2
  • Jane Shearer3
  • Leanne M. Redman4
  • Jeff Smith2
  • Kristi B. Adamo1
4 affiliations
  1. 1School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada
  2. 2Department of Chemistry, Carleton University, Ottawa, ON, Canada
  3. 3Department of Biochemistry and Molecular Biology, Cumming School of Medicine & Faculty of Kinesiology; Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB. Canada
  4. 4Division of Clinical Sciences, Pennington Biomedical Research Center, Baton Rouge, LA, USA
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Abstract

This paper provides novel insight into the placental lipidome in relation to physical activity status in uncomplicated pregnancies. Lipid profiles differ significantly between physically active and inactive groups. Several lipids containing DHA, an essential omega-3 fatty acid with critical roles in fetal brain development, were found to be higher in placentas from active pregnancies. Thirty-four differentially expressed lipids were identified, highlighting future avenues for exploring how physical activity impacts pregnancy outcomes.

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Cite

BibTeXRIS
BibTeX
@article{macdonald2026exploring,
  title = {{Exploring the Placental Lipidome in Physically Active vs. Inactive Pregnancies}},
  author = {Meaghan L. MacDonald and Anahita Yadegari and Justine T. Chittaro and Arthur Dantas and Karl Wasslen and Christian A. Rosales and Jane Shearer and Leanne M. Redman and Jeff Smith and Kristi B. Adamo},
  journal = {Journal of applied physiology (Bethesda, Md. : 1985)},
  year = {2026},
  month = sep,
  doi = {10.1152/japplphysiol.00357.2026},
  url = {https://doi.org/10.1152/japplphysiol.00357.2026},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Exploring the Placental Lipidome in Physically Active vs. Inactive Pregnancies
AU  - Meaghan L. MacDonald
AU  - Anahita Yadegari
AU  - Justine T. Chittaro
AU  - Arthur Dantas
AU  - Karl Wasslen
AU  - Christian A. Rosales
AU  - Jane Shearer
AU  - Leanne M. Redman
AU  - Jeff Smith
AU  - Kristi B. Adamo
PY  - 2026
DA  - 2026/09/14
JO  - Journal of applied physiology (Bethesda, Md. : 1985)
DO  - 10.1152/japplphysiol.00357.2026
UR  - https://doi.org/10.1152/japplphysiol.00357.2026
AB  - This paper provides novel insight into the placental lipidome in relation to physical activity status in uncomplicated pregnancies. Lipid profiles differ significantly between physically active and inactive groups. Several lipids containing DHA, an essential omega-3 fatty acid with critical roles in fetal brain development, were found to be higher in placentas from active pregnancies. Thirty-four differentially expressed lipids were identified, highlighting future avenues for exploring how physical activity impacts pregnancy outcomes.
SN  - 8750-7587
SN  - 1522-1601
ER  -