Traditional Chinese medicine core medication patterns for type 2 diabetes mellitus and their implications for dietary nursing
Abstract
ObjectiveTo reveal the core medication patterns and potential mechanisms of traditional Chinese medicine(TCM) in treating type 2 diabetes mellitus(T2DM),and to analyze their implications for dietary nursing.MethodsClinical research literature on TCM treatment for T2DM was systematically retrieved to establish a prescription database.Data mining and network pharmacology approaches were employed to screen key active components,core targets,and related pathways.Implications for dietary nursing were analyzed based on the distribution characteristics of active components.ResultsA total of 687 clinical research articles on TCM treatment for T2DM were included,involving 319 herbal medicines with 7 684 total medication records.Astragali Radix,Poria,Dioscoreae Rhizoma,Coptidis Rhizoma,Puerariae Lobatae Radix,Atractylodis Macrocephalae Rhizoma,Salviae Miltiorrhizae Radix et Rhizoma,Ophiopogonis Radix,and Codonopsis Radix were identified as core herbs.Network pharmacology analysis indicated that luteolin,formononetin,and quercetin were potential key active components,while AKT1,STAT3,MAPK1,MAPK3 and JUN were potential core targets.ConclusionsTCM treatment for T2DM has formed a relatively clear core medication structure.Network pharmacology reveals three major directions of action:metabolic regulation,inflammatory response modulation,and oxidative stress relief.The distribution characteristics of these key active components in plant⁃derived foods may provide references for nursing staff in dietary guidance and health education during long⁃term diabetes management.
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BibTeX
@article{xinrui2026traditional,
title = {{Traditional Chinese medicine core medication patterns for type 2 diabetes mellitus and their implications for dietary nursing}},
author = {PANG Xinrui and HAN Shifan and GUO Dandan and ZHAO Yiwen},
journal = {Huli yanjiu},
year = {2026},
month = oct,
url = {http://hlyj.suo1.cn/thesisDetails#10.12102/j.issn.1009-6493.2026.21.020},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Traditional Chinese medicine core medication patterns for type 2 diabetes mellitus and their implications for dietary nursing
AU - PANG Xinrui
AU - HAN Shifan
AU - GUO Dandan
AU - ZHAO Yiwen
PY - 2026
DA - 2026/10/30
JO - Huli yanjiu
UR - http://hlyj.suo1.cn/thesisDetails#10.12102/j.issn.1009-6493.2026.21.020
AB - ObjectiveTo reveal the core medication patterns and potential mechanisms of traditional Chinese medicine(TCM) in treating type 2 diabetes mellitus(T2DM),and to analyze their implications for dietary nursing.MethodsClinical research literature on TCM treatment for T2DM was systematically retrieved to establish a prescription database.Data mining and network pharmacology approaches were employed to screen key active components,core targets,and related pathways.Implications for dietary nursing were analyzed based on the distribution characteristics of active components.ResultsA total of 687 clinical research articles on TCM treatment for T2DM were included,involving 319 herbal medicines with 7 684 total medication records.Astragali Radix,Poria,Dioscoreae Rhizoma,Coptidis Rhizoma,Puerariae Lobatae Radix,Atractylodis Macrocephalae Rhizoma,Salviae Miltiorrhizae Radix et Rhizoma,Ophiopogonis Radix,and Codonopsis Radix were identified as core herbs.Network pharmacology analysis indicated that luteolin,formononetin,and quercetin were potential key active components,while AKT1,STAT3,MAPK1,MAPK3 and JUN were potential core targets.ConclusionsTCM treatment for T2DM has formed a relatively clear core medication structure.Network pharmacology reveals three major directions of action:metabolic regulation,inflammatory response modulation,and oxidative stress relief.The distribution characteristics of these key active components in plant⁃derived foods may provide references for nursing staff in dietary guidance and health education during long⁃term diabetes management.
SN - 1009-6493
ER -