Locally Advanced Primary Cervical Endometrial Stromal Sarcoma: A Case Report.
- 1Medical Oncology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University of Oujda, Oujda, MAR.
Abstract
Primary cervical endometrial stromal sarcoma (ESS) is a challenging mesenchymal neoplasm that may present with non-specific clinical manifestations and advanced local disease at diagnosis. We report the case of a 50-year-old diabetic woman presenting with metrorrhagia and pelvic pain. Clinical examination revealed a large ulcerative cervical mass infiltrating the vaginal walls. Histopathology with immunohistochemistry supported the diagnosis of ESS. Imaging demonstrated extensive loco-regional invasion of the bladder, lower vagina, and rectal wall, consistent with FIGO stage IVA disease. The patient was treated with systemic chemotherapy (carboplatin-paclitaxel). This case highlights the diagnostic challenges of cervical ESS, the importance of histopathological and immunohistochemical evaluation, and the therapeutic considerations in locally advanced disease.
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BibTeX
@article{bali2026locally,
title = {{Locally Advanced Primary Cervical Endometrial Stromal Sarcoma: A Case Report.}},
author = {Asmae Bali and Kaouthar Khater and Fadoua Jebrouni and Hind Chibani and Ouissam Al Jarroudi and Sami Aziz Brahmi and Said Afqir},
journal = {Cureus},
year = {2026},
month = sep,
doi = {10.7759/cureus.116888},
url = {https://europepmc.org/article/MED/42928860},
note = {CC BY},
}
RIS
TY - JOUR
TI - Locally Advanced Primary Cervical Endometrial Stromal Sarcoma: A Case Report.
AU - Asmae Bali
AU - Kaouthar Khater
AU - Fadoua Jebrouni
AU - Hind Chibani
AU - Ouissam Al Jarroudi
AU - Sami Aziz Brahmi
AU - Said Afqir
PY - 2026
DA - 2026/09/25
JO - Cureus
DO - 10.7759/cureus.116888
UR - https://europepmc.org/article/MED/42928860
AB - Primary cervical endometrial stromal sarcoma (ESS) is a challenging mesenchymal neoplasm that may present with non-specific clinical manifestations and advanced local disease at diagnosis. We report the case of a 50-year-old diabetic woman presenting with metrorrhagia and pelvic pain. Clinical examination revealed a large ulcerative cervical mass infiltrating the vaginal walls. Histopathology with immunohistochemistry supported the diagnosis of ESS. Imaging demonstrated extensive loco-regional invasion of the bladder, lower vagina, and rectal wall, consistent with FIGO stage IVA disease. The patient was treated with systemic chemotherapy (carboplatin-paclitaxel). This case highlights the diagnostic challenges of cervical ESS, the importance of histopathological and immunohistochemical evaluation, and the therapeutic considerations in locally advanced disease.
SN - 2168-8184
ER -