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Peer-reviewedCC BY-NC-NDJACC. Case reports

Postpartum Left Main Spontaneous Coronary Artery Dissection With Shock, Requiring Surgery and Extracorporeal Membrane Oxygenation.

  1. 1Department of Cardiology, Te Whatu Ora-Health New Zealand, Waitemata, Auckland, New Zealand.
  2. 2Department of Cardiology, Te Whatu Ora-Health New Zealand, Waitemata, Auckland, New Zealand. Electronic address: [email protected].

Abstract

Background

Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome in young women; pregnancy-associated SCAD disproportionately involves the left main coronary artery (LMCA) and cardiogenic shock.Case summary

A 34-year-old woman, 3 months postpartum, presented with collapse and chest pain 2 days after resuming menses. Angiography revealed extensive LMCA dissection extending into the left anterior descending and circumflex arteries. Rapid hemodynamic deterioration necessitated emergency bypass grafting and central venoarterial extracorporeal membrane oxygenation for cardiogenic shock. Her course was complicated by pericardial hematoma and pneumonia; she was weaned from mechanical support with ejection fraction recovery to 50%-55%.Discussion

This case represents an exceptionally rare pregnancy-associated SCAD phenotype combining LMCA involvement, cardiogenic shock, and revascularization.Take-home message

Preserved left ventricular function does not exclude impending collapse in LMCA SCAD; menstrual resumption may be an under-recognized hormonal precipitant of pregnancy-associated SCAD; and meaningful recovery is achievable with prompt, multidisciplinary management.

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BibTeX
@article{somali2026postpartum,
  title = {{Postpartum Left Main Spontaneous Coronary Artery Dissection With Shock, Requiring Surgery and Extracorporeal Membrane Oxygenation.}},
  author = {Mona Al Somali and Rahul Gandhi and Syeda Nitasha Yousaf and Robert Michael and Timothy Glenie and Ali Khan},
  journal = {JACC. Case reports},
  year = {2026},
  month = oct,
  doi = {10.1016/j.jaccas.2026.110284},
  url = {https://europepmc.org/article/MED/42847572},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Postpartum Left Main Spontaneous Coronary Artery Dissection With Shock, Requiring Surgery and Extracorporeal Membrane Oxygenation.
AU  - Mona Al Somali
AU  - Rahul Gandhi
AU  - Syeda Nitasha Yousaf
AU  - Robert Michael
AU  - Timothy Glenie
AU  - Ali Khan
PY  - 2026
DA  - 2026/10/01
JO  - JACC. Case reports
DO  - 10.1016/j.jaccas.2026.110284
UR  - https://europepmc.org/article/MED/42847572
AB  - Background  Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome in young women; pregnancy-associated SCAD disproportionately involves the left main coronary artery (LMCA) and cardiogenic shock.Case summary  A 34-year-old woman, 3 months postpartum, presented with collapse and chest pain 2 days after resuming menses. Angiography revealed extensive LMCA dissection extending into the left anterior descending and circumflex arteries. Rapid hemodynamic deterioration necessitated emergency bypass grafting and central venoarterial extracorporeal membrane oxygenation for cardiogenic shock. Her course was complicated by pericardial hematoma and pneumonia; she was weaned from mechanical support with ejection fraction recovery to 50%-55%.Discussion  This case represents an exceptionally rare pregnancy-associated SCAD phenotype combining LMCA involvement, cardiogenic shock, and revascularization.Take-home message  Preserved left ventricular function does not exclude impending collapse in LMCA SCAD; menstrual resumption may be an under-recognized hormonal precipitant of pregnancy-associated SCAD; and meaningful recovery is achievable with prompt, multidisciplinary management.
SN  - 2666-0849
ER  -