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Peer-reviewedCC BYCase reports in cardiology

Silent Invasion: Isolated Right Ventricular Metastasis from Hepatocellular Carcinoma Diagnosed by Transvenous Biopsy.

  • Mounika Reddy Vadiyala1
  • Sehajpreet Singh2
  • Azka Naeem1
  • Hakob Harutyunyan1
  • Supraja Achuthanandan2
  • David J Epstein2
  • Jasveen Kaur1
  • Vijay Shetty2
  • Simon Thein2
  • Gerald Hollander2
  • Jacob Shani2
  1. 1Department of Internal Medicine Maimonides Medical Center Brooklyn New York USA maimonidesmed.org.
  2. 2Department of Cardiology Maimonides Medical Center Brooklyn New York USA maimonidesmed.org.
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Abstract

Although cardiac involvement is extremely uncommon, hepatocellular carcinoma (HCC) frequently spreads to the lungs, lymph nodes, bones, and adrenal glands. The right atrium is usually affected when there is cardiac involvement because of direct invasion through the inferior vena cava. We report a 71-year-old man who had exertional dyspnea and a rare presentation of HCC metastasizing to the right ventricle (RV). A sizable RV mass with septal infiltration was seen on imaging. A transvenous biopsy confirmed metastatic HCC. After starting systemic therapy again, the patient reported that their clinical condition was stable. This case underscores the value of a multidisciplinary approach to diagnosis and treatment, as well as the diagnostic utility of cardiac biopsy in assessing uncommon cardiac masses.

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Cite

BibTeXRIS
BibTeX
@article{vadiyala2026silent,
  title = {{Silent Invasion: Isolated Right Ventricular Metastasis from Hepatocellular Carcinoma Diagnosed by Transvenous Biopsy.}},
  author = {Mounika Reddy Vadiyala and Sehajpreet Singh and Azka Naeem and Hakob Harutyunyan and Supraja Achuthanandan and David J Epstein and Jasveen Kaur and Vijay Shetty and Simon Thein and Gerald Hollander and Jacob Shani},
  journal = {Case reports in cardiology},
  year = {2026},
  month = oct,
  doi = {10.1155/cric/8832106},
  url = {https://europepmc.org/article/MED/42959486},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Silent Invasion: Isolated Right Ventricular Metastasis from Hepatocellular Carcinoma Diagnosed by Transvenous Biopsy.
AU  - Mounika Reddy Vadiyala
AU  - Sehajpreet Singh
AU  - Azka Naeem
AU  - Hakob Harutyunyan
AU  - Supraja Achuthanandan
AU  - David J Epstein
AU  - Jasveen Kaur
AU  - Vijay Shetty
AU  - Simon Thein
AU  - Gerald Hollander
AU  - Jacob Shani
PY  - 2026
DA  - 2026/10/28
JO  - Case reports in cardiology
DO  - 10.1155/cric/8832106
UR  - https://europepmc.org/article/MED/42959486
AB  - Although cardiac involvement is extremely uncommon, hepatocellular carcinoma (HCC) frequently spreads to the lungs, lymph nodes, bones, and adrenal glands. The right atrium is usually affected when there is cardiac involvement because of direct invasion through the inferior vena cava. We report a 71-year-old man who had exertional dyspnea and a rare presentation of HCC metastasizing to the right ventricle (RV). A sizable RV mass with septal infiltration was seen on imaging. A transvenous biopsy confirmed metastatic HCC. After starting systemic therapy again, the patient reported that their clinical condition was stable. This case underscores the value of a multidisciplinary approach to diagnosis and treatment, as well as the diagnostic utility of cardiac biopsy in assessing uncommon cardiac masses.
SN  - 2090-6404
SN  - 2090-6412
ER  -