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Peer-reviewedCC BY-NC-NDThe Indian journal of radiology & imaging

Understanding AI Algorithms in Medical Imaging: A Radiologist's Guide to Models and Methods.

  1. 1Department of RadiologyKokilaben HospitalMumbaiMaharashtraIndia.
  2. 2Department of Radiology and ImagingJay Prabha Medanta Super Specialty HospitalPatnaBiharIndia.

Abstract

Artificial intelligence is now embedded in radiology workflows across detection, triage, quantification, and reporting. Yet, most clinicians deploy these tools without a working understanding of how their outputs are generated or where they reliably fail. Unlike conventional rule-based clinical workflows, modern imaging AI systems generate probabilistic outputs whose reliability depends on training data, task definition, and deployment context. Radiologists must understand what these systems actually produce, know their predictable failure points, and never allow a confidence score to replace the clinical reasoning that only a trained human can apply. This review provides a clinician-oriented framework for understanding imaging AI by covering core model architectures, task-based applications, workflow integration, and the practical interpretation of algorithmic outputs. This is important because as imaging AI scales across institutions and populations, the radiologist's capacity to interrogate, contextualize, and, where necessary, override algorithmic outputs becomes not just a clinical skill but a professional responsibility.

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BibTeX
@article{maheshwari2026understanding,
  title = {{Understanding AI Algorithms in Medical Imaging: A Radiologist's Guide to Models and Methods.}},
  author = {Sharad Maheshwari and Sachin Kumar},
  journal = {The Indian journal of radiology \& imaging},
  year = {2026},
  month = sep,
  doi = {10.1055/s-0046-1829014},
  url = {https://europepmc.org/article/MED/42921647},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Understanding AI Algorithms in Medical Imaging: A Radiologist's Guide to Models and Methods.
AU  - Sharad Maheshwari
AU  - Sachin Kumar
PY  - 2026
DA  - 2026/09/11
JO  - The Indian journal of radiology & imaging
DO  - 10.1055/s-0046-1829014
UR  - https://europepmc.org/article/MED/42921647
AB  - Artificial intelligence is now embedded in radiology workflows across detection, triage, quantification, and reporting. Yet, most clinicians deploy these tools without a working understanding of how their outputs are generated or where they reliably fail. Unlike conventional rule-based clinical workflows, modern imaging AI systems generate probabilistic outputs whose reliability depends on training data, task definition, and deployment context. Radiologists must understand what these systems actually produce, know their predictable failure points, and never allow a confidence score to replace the clinical reasoning that only a trained human can apply. This review provides a clinician-oriented framework for understanding imaging AI by covering core model architectures, task-based applications, workflow integration, and the practical interpretation of algorithmic outputs. This is important because as imaging AI scales across institutions and populations, the radiologist's capacity to interrogate, contextualize, and, where necessary, override algorithmic outputs becomes not just a clinical skill but a professional responsibility.
SN  - 0971-3026
SN  - 1998-3808
ER  -