Efficacy analysis of the Turnbull–Cutait procedure in refractory perianal Crohn’s disease: a two-centre retrospective study
- 1Department of Colorectal and Anal Surgery, Inflammatory Bowel Disease Surgical Diagnosis and Treatment Center, Zhongnan Hospital of Wuhan University, Wuhan, 430071 China
- 2Department of General Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510655 China
Abstract
Purpose: Patients with refractory perianal Crohn’s disease (RpCD) often face rectal resection and permanent ostomy as a final resort. The Turnbull–Cutait (TC) pull-through procedure offers a potential sphincter-preserving alternative, yet evidence supporting its use in RpCD remains scarce. This study evaluated the therapeutic efficacy of the TC procedure in this setting.
Methods: A retrospective analysis was conducted on ten patients with RpCD who planned to undergo TC surgery at Zhongnan Hospital of Wuhan University and the Sixth Affiliated Hospital of Sun Yat-sen University from January 2020 to June 2025; ultimately, eight patients completed the surgery. The median follow-up duration was 14.5 months.
Results: In the per-protocol analysis (n = 8), the incidence of postoperative complications during follow-up was 37.5%, including 1 case of anal fistula recurrence, 1 case of anal incontinence, and 1 case of rectovaginal fistula recurrence. Five patients achieved short-term technical success, yielding a short-term technical success rate of 62.5%. Their median gastrointestinal quality of life index (GIQLI) score was 138 points, indicating an overall high quality of life.
Conclusion: The TC procedure may serve as a salvage option to avoid permanent stoma in strictly selected patients with RpCD. Although short-term clinical improvement was observed in some patients, the relatively high complication rate and an uncertain long-term efficacy warrant cautious application and careful patient selection.
Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s00384-026-05148-0.
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BibTeX
@article{tu2026efficacy,
title = {{Efficacy analysis of the Turnbull–Cutait procedure in refractory perianal Crohn’s disease: a two-centre retrospective study}},
author = {Qianwen Tu and Huanxin Hu and Mengting Zhang and Kangcheng Luo and Songlin Wan and Daojiang Li and Yi Li and Jia Ke and Zhao Ding},
journal = {International Journal of Colorectal Disease},
year = {2026},
month = may,
doi = {10.1007/s00384-026-05148-0},
url = {https://doi.org/10.1007/s00384-026-05148-0},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Efficacy analysis of the Turnbull–Cutait procedure in refractory perianal Crohn’s disease: a two-centre retrospective study
AU - Qianwen Tu
AU - Huanxin Hu
AU - Mengting Zhang
AU - Kangcheng Luo
AU - Songlin Wan
AU - Daojiang Li
AU - Yi Li
AU - Jia Ke
AU - Zhao Ding
PY - 2026
DA - 2026/05/14
JO - International Journal of Colorectal Disease
DO - 10.1007/s00384-026-05148-0
UR - https://doi.org/10.1007/s00384-026-05148-0
AB - Purpose: Patients with refractory perianal Crohn’s disease (RpCD) often face rectal resection and permanent ostomy as a final resort. The Turnbull–Cutait (TC) pull-through procedure offers a potential sphincter-preserving alternative, yet evidence supporting its use in RpCD remains scarce. This study evaluated the therapeutic efficacy of the TC procedure in this setting. Methods: A retrospective analysis was conducted on ten patients with RpCD who planned to undergo TC surgery at Zhongnan Hospital of Wuhan University and the Sixth Affiliated Hospital of Sun Yat-sen University from January 2020 to June 2025; ultimately, eight patients completed the surgery. The median follow-up duration was 14.5 months. Results: In the per-protocol analysis (n = 8), the incidence of postoperative complications during follow-up was 37.5%, including 1 case of anal fistula recurrence, 1 case of anal incontinence, and 1 case of rectovaginal fistula recurrence. Five patients achieved short-term technical success, yielding a short-term technical success rate of 62.5%. Their median gastrointestinal quality of life index (GIQLI) score was 138 points, indicating an overall high quality of life. Conclusion: The TC procedure may serve as a salvage option to avoid permanent stoma in strictly selected patients with RpCD. Although short-term clinical improvement was observed in some patients, the relatively high complication rate and an uncertain long-term efficacy warrant cautious application and careful patient selection. Supplementary Information: The online version contains supplementary material available at https://doi.org/10.1007/s00384-026-05148-0.
SN - 0179-1958
SN - 1432-1262
ER -