Regulatory mechanisms of fruit ripening: an insight into DNA, histone, and RNA modifications
Abstract
Complex regulatory networks formed by epigenetic modifications such as DNA, histones, and RNA can influence gene expression without altering DNA sequences, participating in ripening processes and quality changes in fruits. Although significant progress has been made in understanding epigenetic modifications and their roles in fruit ripening, the regulatory network underlying these complex relationships remains incompletely elucidated. Here, we summarize the key molecular regulatory networks involving DNA, histone, and RNA modifications in fruit ripening and secondary metabolite changes in recent years; review the research applications of epigenetic modification inhibitors and omics technologies, elucidating their advantages and limitations; and ultimately propose a comprehensive strategic model for future studies on epigenetic modification regulation of fruit ripening. These findings not only deepen our understanding of epigenetic modifications during fruit ripening but also raise new questions and research directions. It provides a deeper understanding of the ripening process and quality changes in fruits, offering insights for new strategies in fruit production and integrated regulation.
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BibTeX
@article{zhai2026regulatory,
title = {{Regulatory mechanisms of fruit ripening: an insight into DNA, histone, and RNA modifications}},
author = {Tingkai Zhai and Chenwen Zhou and Fei Xie and Yudie Chen and Jiayi Chen and Zimeng Yang and Sijia Yang and Honglu Hu and Shaojia Li and Jinping Cao and Yue Wang and Chongde Sun},
journal = {Horticulture research},
year = {2026},
month = may,
doi = {10.1093/hr/uhag235},
url = {https://europepmc.org/article/PMC/PMC13723082},
note = {CC BY},
}
RIS
TY - JOUR
TI - Regulatory mechanisms of fruit ripening: an insight into DNA, histone, and RNA modifications
AU - Tingkai Zhai
AU - Chenwen Zhou
AU - Fei Xie
AU - Yudie Chen
AU - Jiayi Chen
AU - Zimeng Yang
AU - Sijia Yang
AU - Honglu Hu
AU - Shaojia Li
AU - Jinping Cao
AU - Yue Wang
AU - Chongde Sun
PY - 2026
DA - 2026/05/20
JO - Horticulture research
DO - 10.1093/hr/uhag235
UR - https://europepmc.org/article/PMC/PMC13723082
AB - Complex regulatory networks formed by epigenetic modifications such as DNA, histones, and RNA can influence gene expression without altering DNA sequences, participating in ripening processes and quality changes in fruits. Although significant progress has been made in understanding epigenetic modifications and their roles in fruit ripening, the regulatory network underlying these complex relationships remains incompletely elucidated. Here, we summarize the key molecular regulatory networks involving DNA, histone, and RNA modifications in fruit ripening and secondary metabolite changes in recent years; review the research applications of epigenetic modification inhibitors and omics technologies, elucidating their advantages and limitations; and ultimately propose a comprehensive strategic model for future studies on epigenetic modification regulation of fruit ripening. These findings not only deepen our understanding of epigenetic modifications during fruit ripening but also raise new questions and research directions. It provides a deeper understanding of the ripening process and quality changes in fruits, offering insights for new strategies in fruit production and integrated regulation.
SN - 2662-6810
SN - 2052-7276
ER -