Bacterial dispersal and host specificity shape microbiome strain sharing among great ape species in neighboring zoo exhibits
- 1Max Planck Institute for Evolutionary Anthropology
Abstract
Animal microbiomes often exhibit host-species-specific structure, which could suggest a shared evolutionary history with their hosts. However, in wild populations this possibility has been difficult to disentangle from geographic or ecological barriers to microbial dispersal, particularly in taxa like non-human primates in which phylogeny and geography are closely related. To investigate microbiome transmission and adaptation in a common environment, the gut microbiomes of zoo-housed great apes were profiled longitudinally for four months. Even in a shared environment, phylogenetic structure emerged in both species- and strain-level microbiome composition. Longitudinal tracking of new strain acquisitions revealed that transmission across exhibits was possible, even between distantly related host species, suggesting that phylogenetic structure emerged in the longer term as different strains survived in different hosts. Comparison to metagenomes from humans and wild great apes revealed little evidence that human keepers, researchers, or zoo guests drive transmission between exhibits. Instead, across-exhibit transmission disproportionately involved spore-forming bacterial genera, possibly suggesting airborne spore transmission as a means of bacterial dispersal. By investigating microbiomes of different host species in a common geographic environment without direct inter-host interaction, this study identifies spatial constraints on transmission, bacterial dispersal ability, and differential survival of bacterial strains in different hosts as factors shaping the gut microbiomes of great apes.
Related
- Host specificity, seasonality, and urbanicity shape the gut microbiome of a synanthropic insect
- High variability and limited host specificity characterise the microbiome of Desmophyllum pertusum across a cold-water coral reef
- A GacS-mediated regulatory framework coordinates bacterial competition and rhizosphere microbiome remodeling in Pseudomonas fluorescens
- Large-scale metagenomic characterization of the vaginal microbiome and uropathogens in women with recent bacterial vaginosis and urinary tract infections
- Perturbation-based propagation of bacterial composition uncertainty improves robustness and reproducibility of microbiome differential abundance analysis.
BibTeX
@misc{krauss2026bacterial,
title = {{Bacterial dispersal and host specificity shape microbiome strain sharing among great ape species in neighboring zoo exhibits}},
author = {P. Krauss and A. Breier and A.-L. Hohlfeld and H. Keller and V. Kunkel and M. Meier and S. Plettemeier and W. Thomas and R. Debray},
howpublished = {bioRxiv},
year = {2026},
month = oct,
doi = {10.64898/2026.10.06.757053},
url = {https://www.biorxiv.org/content/10.64898/2026.10.06.757053v1},
note = {CC BY-ND},
}
RIS
TY - UNPB
TI - Bacterial dispersal and host specificity shape microbiome strain sharing among great ape species in neighboring zoo exhibits
AU - P. Krauss
AU - A. Breier
AU - A.-L. Hohlfeld
AU - H. Keller
AU - V. Kunkel
AU - M. Meier
AU - S. Plettemeier
AU - W. Thomas
AU - R. Debray
PY - 2026
DA - 2026/10/06
PB - bioRxiv
DO - 10.64898/2026.10.06.757053
UR - https://www.biorxiv.org/content/10.64898/2026.10.06.757053v1
AB - Animal microbiomes often exhibit host-species-specific structure, which could suggest a shared evolutionary history with their hosts. However, in wild populations this possibility has been difficult to disentangle from geographic or ecological barriers to microbial dispersal, particularly in taxa like non-human primates in which phylogeny and geography are closely related. To investigate microbiome transmission and adaptation in a common environment, the gut microbiomes of zoo-housed great apes were profiled longitudinally for four months. Even in a shared environment, phylogenetic structure emerged in both species- and strain-level microbiome composition. Longitudinal tracking of new strain acquisitions revealed that transmission across exhibits was possible, even between distantly related host species, suggesting that phylogenetic structure emerged in the longer term as different strains survived in different hosts. Comparison to metagenomes from humans and wild great apes revealed little evidence that human keepers, researchers, or zoo guests drive transmission between exhibits. Instead, across-exhibit transmission disproportionately involved spore-forming bacterial genera, possibly suggesting airborne spore transmission as a means of bacterial dispersal. By investigating microbiomes of different host species in a common geographic environment without direct inter-host interaction, this study identifies spatial constraints on transmission, bacterial dispersal ability, and differential survival of bacterial strains in different hosts as factors shaping the gut microbiomes of great apes.
ER -